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Early diagnosis of major brain diseases, especially in children, is a crucial yet largely unmet clinical need. Since 1996 Aston University researchers have pioneered the development and clinical application of Magnetoencephalography (MEG). The team's research now supports the UK's first and largest clinical pre-surgical evaluation programme in partnership with leading neurosurgery centres. This work has had the following impacts (2008 — date) on health services, patient welfare and commerce:
Research conducted by Carol Holland for the Department for Transport (DfT, 2001 - 2004) contributed to a shift in public and professional attitude, stereotypes, and to revised international guidelines that recommend encouragement of self-regulation by older drivers. Furthermore, accurate pedestrian simulation methods were developed (2007 - 2010) which led to European interventions addressing the safety of older pedestrians. Improved advice to older road users has encouraged safe-mobility and social inclusion. Thus, we describe significant impact on:
Research by the University of Huddersfield has helped shape policy and practice in the field of surgical site infection (SSI) and wound management. It has contributed to best practice guidance and helped to raise practitioner, industry and public awareness of the importance of effective clinical interventions in infection prevention, tissue viability and wound care. These efforts, recognised by numerous awards, have been supported by significant industry engagement and the successful development and use of on-line tools to share best practice, promote evidence-based care and highlight the value of an inter-disciplinary approach to the problem of SSI.
Increased understanding of how a member state can influence the EU created two kinds of impacts: changing thinking, understanding and awareness (e.g. HM Treasury); and changing strategy and policy (e.g. EU Committee of Regions). Impacts were generated between 2008 and 2012 on the Polish Government, the Swedish International Development Agency, the US Depository Trust and Clearing Corporation, civil servants in Ukraine, Russia and the UK, the European think tank community, the Labour Party and the EU's Committee of the Regions. Impact was generated through consultancies to public bodies and by providing advice to governments, international organisations and the private sector.
Metformin is now the most prescribed medication for type 2 diabetes worldwide. Pre - 1990 it received trivial use and was on the verge of withdrawal. Research at Aston (1993 - 1996) generated a new appreciation of its mechanisms of action and therapeutic potential. Aston research was reinforced with a concerted education programme for healthcare professionals, including high-profile reviews and treatment guidelines. We claim impact on health & welfare and health practitioners as Aston research has provided a foundation for improved care of type 2 diabetes patients on a global scale.
`Cold War Modern. Design 1945-1970' (CWM) was a four-year research project exploring the impact of the cold war on modern art, architecture and design. Conceived, researched and curated as a major exhibition by Professors David Crowley and Jane Pavitt, it provided new interpretations of the history of design in the second half of the 20th century for a wide public, international audience. The exhibition was reviewed around the world and was acquired — as a `package' of concept, exhibits and publications — by venues abroad. We are claiming impact in the fields of public and media understanding of post-Second World War cultural history and on the curatorial and collecting activities of museums around the world.