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The use and treatment of animals in the provision of our food, clothing and other raw materials, as well as in the areas of medical research, sport and entertainment, polarises public opinion and provokes extreme views. Research by Professor Robert Garner on the ethics and politics of animal protection has provided a springboard for political debate and decision making both in the UK and internationally. In particular, Garner's work has impacted upon the debate within the animal protection movement, and has helped to shape aspects of government policy on animal welfare issues in general, most notably on the UK Government's approach to the issue of whaling, and DEFRA's approach to the ethics of using wild animals in circuses.
The UK infant formula market increased in value from 2005-2013 by 65% to £463m. The Unit's research, funded by the Food Standards Agency and the Department of Health, addressed the concerns of policy makers and breast feeding lobby groups that baby food manufacturers might be circumventing recently introduced restrictions on advertising infant formula (breast milk substitute) products in such a way as to undermine support for, and uptake of, breastfeeding. The research findings underpinned the recommendations on regulatory change made to government by an independent review panel established by the Minister of State for Public Health. Since the panel reported, manufacturers have addressed the issue by removing publicly accessible links to infant formula product information.
Trauma is a rapidly increasing global healthcare problem which is predicted by the World Health Organisation (WHO) to overtake infectious disease globally by 2020. The discovery of the acute coagulopathy of trauma (uncontrolled bleeding) and the subsequent establishment of the clot stabiliser tranexamic acid (TXA) as a treatment for this condition has led to a change in national and international trauma management protocols. British armed forces and the US military implemented the use of the drug soon after the results were published. Every injured British or American soldier now receives this treatment. The use of TXA has been included in national and international guidance for trauma care.
Asthma and Chronic Obstructive Pulmonary Disease (COPD) are common, global diseases which cause considerable morbidity and mortality. Worldwide, around 235 million people suffer from asthma, while COPD accounts for 3 million, or 5% of all, global deaths, according to the World Health Organization (WHO). The relationship between inflammation and airway dysfunction is central to an understanding of their pathogenesis and treatment. The respiratory medicine group in the Department of Infection, Immunity and Inflammation has shown that optimal management of these conditions requires measurement of airway inflammation to stratify treatment regimes, an approach incorporated into national guidelines in 2012. In the late 1990s the group characterised a new clinical syndrome: `eosinophilic bronchitis', which is one of the commonest causes of chronic cough. The group's work has helped to launch a new class of drugs for asthma and to change the conceptual framework by which anti-inflammatory drugs for asthma are being developed.
The impact comes from Ekserdjian's authentication and attribution of Renaissance paintings and the curatorship of international exhibitions, both of which have had substantial financial impact on institutions and individuals involved in the art market, in particular the auction house sector, galleries and museums. This also includes cultural impacts on the art-loving public by introducing them to newly-discovered and attributed artworks which might previously have never been exhibited publicly and by offering innovative ways of exhibiting and understanding masterpieces gathered from around the globe.
In August 2010 the UNESCO World Heritage Committee inscribed 11 Australian Convict Sites onto its World Heritage list. Anderson was a member of the Australian Government's small expert reference and nomination groups; her unique knowledge of the global history of convict transportation and penal colonies around the world during the period 1780-1939 provided the essential comparative analysis necessary to underpin the Australian government's claim that the Australian sites were globally unique and unparalleled, and so to prepare the final nomination to UNESCO. The inscription of these new World Heritage sites paved the way for significant tourist development, as well as important social and cultural changes to the heritage sector's representation of Australia's convict history.
Stroke is the third most common cause of death and single most important cause of adult disability in the UK, affecting over 150,000 individuals per annum and costing the economy approximately £8 billion annually in health, social and indirect care costs.
High blood pressure (BP) is the most common modifiable risk factor to prevent stroke, but the use of BP-lowering therapy in the acute phase of stroke is controversial. Clinical trials co-ordinated at the University of Leicester have confirmed the safety of continuation of pre-existing BP-lowering therapy in acute stroke and the de novo treatment of high blood pressure in acute intracerebral haemorrhage. This has resulted in changes to the most recent US (2013) and UK (2012) guidelines, which will significantly impact on clinical management of this common clinical problem in acute stroke.
Data generated by sensors on-board satellites orbiting the Earth have become extremely important to businesses and public sector organisations. They are the essential ingredient in satellite-enabled consumer services, from GoogleEarth to disaster management, insurance and agriculture. The Earth Observation Science group at Leicester has played a leading role in the transfer of cutting-edge Earth Observation techniques and know-how to the private and public sectors, enabling more businesses to use the technology for commercial gain. Leicester experience in technology translation led to its invited contribution to the UK space industry-led report to government, an Innovation and Growth Strategy for Space.
The Greenwood Institute of Child Health is a unique collaboration between the University and public service providers such as the NHS, which aims to improve psychological outcomes for children in high-risk settings. From 1993 to 2013, Greenwood's research has highlighted the increased risk of mental health, drug dependence and criminal activity among children who suffer trauma — through abuse, living in care, homelessness or war. Greenwood's programme of research has identified the complex and persistent needs of vulnerable children and contributed to changes in policy guidelines and service provision across social care in the UK (foster care / adoption, juvenile detention and homelessness) and abroad (war). Collaboration between researchers at the Greenwood Institute, service providers and practitioners has been instrumental in the establishment of clinically relevant and cost-effective care pathways, while community engagement has led to improved service provision and outcomes for vulnerable children and their families / carers in the UK and further afield.
A research project, embedded in the local community, unearthed multiple Iron Age treasures that have rewritten our understanding of the Iron Age to Roman transition in Britain. The discoveries directly inspired the South East Leicestershire Treasure project (SELT), which raised £934k funding (including 651K from the Heritage Lottery Fund (HLF)) for a major programme encompassing museum redevelopment, travelling exhibitions and a suite of learning resources. SELT initiatives have been enjoyed by over 270,000 members of the public, who through it have gained fascinating insights into our distant past. The find has also inspired a huge sense of community pride in a Leicestershire village and underlined the value of university involvement in local archaeology. The project was another important factor in the recent award of a Queen's Anniversary Prize.