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The University of Southampton's lifecourse cohort studies have led to a paradigm shift in the medical approach to obesity and non-communicable diseases. Research linking maternal pre-conception and early years nutrition with health outcomes for later life has directly influenced public healthcare policy at international (United Nations), national (Scientific Advisory Committee on Nutrition) and local (Southampton City) levels. Dissemination through medical practice and Southampton-designed public education programmes such as LifeLab means this research has already led to health benefits for tens of thousands of people, providing them with the information and tools to help prevent themselves and their children from succumbing to a non-communicable disease.
Omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) are essential nutrients and have many beneficial effects on human health. Fish are the major source of omega-3 LC-PUFA in the human diet, and its level was maintained in farmed fish through the use of fish oil as a major component of extruded aquafeeds. Around 10 years ago it became clear that demand for fish oil would rapidly outstrip supply, limiting expansion of aquaculture activities, if fish oil use was not reduced. The challenge this presented was that alternatives to fish oil lack omega-3 LC-PUFA. However, replacement of fish oil with more sustainable alternatives is now standard practice in the industry. Research into fish oil replacement and omega-3 metabolism in the Nutrition Group, Institute of Aquaculture has been at the forefront of the scientific research in the UK and Europe that has ensured nutritional quality of farmed fish by developing alternative feed ingredients and feeding strategies that have maintained levels of omega-3 LC-PUFA despite radical changes to feed composition driven by sustainability and food security. This work culminated with recent demonstrations that farmed salmon can be net producers of marine protein (2010) and oil (2011).
Research led by Professor Charles Tyler at the University of Exeter has provided critical data on the widespread adverse oestrogenic effects of endocrine disrupting chemicals in wild fish populations in the UK. This has triggered the UK government to take action through investment in research and development of policies and guidelines. The research has led to world-wide recognition that endocrine disrupting chemicals are an emerging policy issue, a £40 million demonstration project with the UK government and water industry, and multi-million pound benefits to the UK in terms of improved water quality and safeguarding freshwater wildlife.
Disease severely limits the expansion of aquaculture. Studies on the immune control of infection have led, in association with industry, to the promotion of disease control utilising 03b2-glucan feed supplements. Knowledge has, via Keele Water, informed infection control strategies used by UK fish farmers. Studies have provided a legacy of young scientists trained by industry and supported by European funding. Advances made have been embraced in the education of veterinarians in Germany and fish production in Eastern Europe. Close collaboration with government bodies and learned societies has ensured that the work has been recognised by policy makers within the fisheries sector.