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Stars ‘r’ Us! Engaging the Public with Astrochemical Research

Summary of the impact

Stars `r' Us! (SRU) is a touring exhibition conceived in 2004 by Professor Martin McCoustra to engage the public with astrochemistry. SRU has been updated frequently, most recently in 2010 to include on-going work at Heriot-Watt University (HWU). SRU has contributed regularly to major science festivals, with independently corroborated strong impact on public attitudes. Over its lifetime, active researchers have interacted directly with an estimated 11,000 visitors, most of whom were teenagers. SRU has further indirect reach through a widely distributed teacher's pack. It is also a valuable element of the public engagement programme at HWU which has seen demonstrably improved recruitment to chemistry programmes over recent years. SRU has engaged with the EU Commission through an ESF co-sponsored event: laboratory astrochemistry has recently achieved preferred status in a Horizon 2020 foresighting exercise.

Submitting Institution

Heriot-Watt University

Unit of Assessment

Chemistry

Summary Impact Type

Societal

Research Subject Area(s)

Physical Sciences: Astronomical and Space Sciences
Chemical Sciences: Analytical Chemistry, Physical Chemistry (incl. Structural)

Empowering Chemists in Africa Through Green Chemistry (CS4)

Summary of the impact

University of Nottingham researchers have been at the forefront in promoting and establishing Green Chemistry in developing nations. Working with and influencing colleagues and policymakers in both the UK and Africa, they have increased awareness of the importance of introducing sustainable technologies that meet local communities' needs. As a result, they have invigorated the chemistry teaching curriculum in Ethiopia, placing Green Chemistry at its core, and helped shape the approaches of professional bodies, including the Royal Society of Chemistry, for the benefit of the developing world. This has led to what the British Council has described as "a sense of empowerment and confidence" among Ethiopian chemists.

Submitting Institution

University of Nottingham

Unit of Assessment

Chemistry

Summary Impact Type

Societal

Research Subject Area(s)

Chemical Sciences: Analytical Chemistry, Organic Chemistry, Physical Chemistry (incl. Structural)

Developing New Approaches for the Safety Assessment of Cosmetics to Replace the Use of Animal testing.

Summary of the impact

The European Union Cosmetics Directive (adopted in 2003) banned the use of animals for testing cosmetic ingredients and the final deadline for compliance was March 2013. The development of alternative methods of safety assessment was therefore essential to ensure both consumer protection and viability of the cosmetics industry. Our research has focussed on the development of computational alternatives to animal testing, including the identification of structural alerts that have been encoded into computational workflows to support toxicity prediction. These methods have delivered tools to the cosmetics industry in Europe and worldwide to enable them to comply with the directive and develop new products. Our findings have also been used to inform thinking and policy in Europe and to develop a new approach to the safety assessment of cosmetics.

Submitting Institution

Liverpool John Moores University

Unit of Assessment

Allied Health Professions, Dentistry, Nursing and Pharmacy

Summary Impact Type

Technological

Research Subject Area(s)

Chemical Sciences: Organic Chemistry, Other Chemical Sciences
Medical and Health Sciences: Pharmacology and Pharmaceutical Sciences

C1 - The Founding of Argenta Discovery and Pulmagen Therapeutics

Summary of the impact

The growth and performance of Biofocus Galapagos Argenta (BGA) and Pulmagen Therapeutics (PT) are underpinned by research from the Imperial-based TeknoMed project that started in 1997. BGA was formed in 2010 through the acquisition of Argenta Discovery (AD) by Biofocus Galapagos for €16.5 million and is one of the world's largest drug discovery service organisations with 390 plus employees and turnover of €135 million [section 5, A]. PT was formed as a separate company to own the complete AD drug pipeline. It develops new medicines to treat asthma, cystic fibrosis and allergic diseases. In 2011 BGA signed agreements with PT for an initial £6million fee and with Genentech for £21.5million.

Submitting Institution

Imperial College London

Unit of Assessment

Chemistry

Summary Impact Type

Technological

Research Subject Area(s)

Chemical Sciences: Inorganic Chemistry, Organic Chemistry, Other Chemical Sciences

CS1 - Innovative chemistry reduces the environmental impact of mining and pharmaceutical manufacture

Summary of the impact

The technology in this impact study is based on organofunctionalised silica materials that can address market needs for high purity in compounds that underpin many areas of the pharma, electronic and medical sectors as well as the recovery of limited resources such as precious metals that are used in diverse industries. Since the launch of the product portfolio in 2006, the materials have become embedded in purification or recovery steps in commercial production processes of leading mining (South Africa), pharmaceutical (UK) and petrochemical (Germany) companies and make a significant impact on the business of these companies as well as limiting waste of limited resources.

Submitting Institution

Queen Mary, University of London

Unit of Assessment

Chemistry

Summary Impact Type

Technological

Research Subject Area(s)

Chemical Sciences: Inorganic Chemistry, Organic Chemistry, Other Chemical Sciences

Multi-million pound sales and efficiency gains through formulation development and process optimisation

Summary of the impact

Significant economic impact was achieved as a result of research into polymer nanocomposites and their formation, conducted at WestCHEM from 2000 to 2010. Collaboration over the six-year period 2004-2010 with Carron Phoenix Ltd, the world's largest manufacturer of composite `granite' kitchen sinks, led to nanocomposite technology being incorporated into over one million sinks, generating income for the company in excess of £50M from 2007 to the present day. Considerable production efficiency gains saved in excess of £1M annually through the reduction in manufacturing time, the reduction of raw materials wastage, and the reduction in landfill costs (and commensurate environmental benefit) for failed and out-of-spec products. In addition, a £4M capital investment by the company at the Falkirk plant was secured, enabling the company to sustain its leading position in the designer kitchen sink market. With the site consequently designated as the parent company's competency centre for composite sink technology, employment for 170 workers was secured.

Submitting Institutions

University of Strathclyde,University of Glasgow

Unit of Assessment

Chemistry

Summary Impact Type

Technological

Research Subject Area(s)

Chemical Sciences: Macromolecular and Materials Chemistry
Engineering: Materials Engineering, Mechanical Engineering

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