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Research carried out at the University of Aberdeen has directly resulted in a new therapy for stroke patients who have suffered partial sight loss. The sight rehabilitation device developed through the research has so far been used to treat around 300 UK stroke patients, who reported significant improvements in their quality of life. The therapy has been publicized by the UK Stroke Association and at national and international events. The research also led to commercial impacts through the creation of a spin-out company, Sight Science Ltd, which was later acquired by its only worldwide competitor, NovaVision Inc, protecting jobs and forging a long-term commercial partnership.
The specific impacts on commerce have been: substantial industrial investment in research and development, job creation and protection within UK industry, commercialisation of a new product, and long term partnership contract with industry with provisions for commercialisation of future products.
Research at the UCL Institute of Ophthalmology over the last 15 years has developed new treatments for management of uveitis and its sight-threatening complications, which have subsequently become standard practice. Our work, in previously untreatable disease, has allowed restoration of vision in many patients and prevention of further visual loss in others. Many patients have been able to reduce systemic medication, limiting adverse effects of treatment.
Research by Dr Alex Leff at the UCL Institute of Neurology in collaboration with UCL Multimedia, has led to the development of two free online therapies for stroke patients with visual deficits. Read-Right (launched June 2010) treats patients with hemianopic alexia (the commonest acquired reading disorder) and Eye-Search (launched September 2012) treats spatial disorientation and visual search impairment. The websites contain: 1) diagnostic tests, 2) therapy, and 3) interval tests. These materials have been developed from peer-reviewed research. The websites are also research tools; patients sign an online consent form and their data are used to test whether online therapy actually works. At 31 July 2013, 657 patients were using Read-Right and 217 Eye-Search.
Dizziness is a common presenting symptom in general practice, neurology, ENT and old age medicine. Chronic dizziness in particular has a major impact on the individual and health service resources. Imperial College researchers have shown that the best treatment, from primary to tertiary care, is balance rehabilitation. Imperial researchers have provided the scientific basis for understanding a common form of chronic dizziness triggered by visual movement, which we labelled and is now known as "visual vertigo". We have developed an effective desensitization treatment program for this condition which is acknowledged in a Department of Health (DoH) "Good practice guide" document in 2009. The new desensitization treatment has now been adopted by rehabilitation professionals worldwide.
Up to 10% of stroke patients experience persistent hemispatial neglect, a lack of perception of space in one half of their visual field, despite their eyesight functioning properly. University of Glasgow researcher Dr. Monika Harvey has led the development of a vision rehabilitation method that was implemented by German stroke units (2011) and applied to over 60 stroke patients. In July 2011 Harvey formulated content for an advanced training module called `Vision after Stroke', a Scottish Government supported online training resource for stroke healthcare professionals provided by the Stroke Training and Awareness Resources (STARs) Project. In just eight months since launch (December 2012) the module series has had 17 473 unique visitors nationally and internationally with `Vision after Stroke' the second most popular module in Scotland. To date, 152 healthcare professionals have successfully completed the `Vision after Stroke' module certificate.
Dizziness is one of the most common presenting symptoms in General Practice, Ear Nose and Throat and neurology clinics. Chronic dizziness in particular has a major impact on individual and health service resources. Researchers at King's College London (KCL) have developed an effective exercise-based rehabilitation programme incorporating optokinetic stimulation to treat a specific form of chronic dizziness, visual vertigo. This programme has been adopted by audiology and physiotherapy services across the UK and is now being adopted internationally and commercialized. The work of KCL researchers is also reflected by inclusion in information and continued educational activities with regard to visual vertigo.
Coordination between the eyes is vital for children's visual and motor development, yet it often fails to develop properly. Horwood and Riddell's research has had important implications for the clinical management of binocular coordination, particularly for infant squint and childhood long-sightedness. They have demonstrated that most newborn infants (approximately 75%) have intermittent misalignment (i.e. sometimes point their eyes in different directions), but after 4 months of age only 3.25% continue to squint and it is only these children that require intervention. As a result, concerned parents have been advised appropriately and unnecessary appointments with GPs and specialists have been reduced. Horwood and Riddell's findings have also led to a substantial change in the management of long-sightedness, from which about 5% of children in the UK suffer (i.e. approximately 300,000 children between 5 and 14 years of age). Traditionally, children with long-sightedness have been provided with glasses that under-correct their vision. Our findings, however, have (i) demonstrated that some long-sighted children choose not to focus on near objects, and (ii) informed clinicians that full correction of focussing is often required to ensure clear vision, for instance, when reading. In both areas, Horwood and Riddell's research has led to changes in clinical guidelines, training, and practice and the advice given to concerned parents.
Falls are a common and serious health risk for older people and reducing falls is a priority for the NHS. Research at the University of Bradford on the link between vision and falls has led to new healthcare guidelines, specifically those from the College of Optometrists and the British Geriatrics Society and endorsed by Age UK and the Royal College of General Practitioners. Continuing professional development practices have changed and public awareness of this health risk has been raised by Which? reports and subsequent media coverage. These developments have impacted on the health and welfare of older people, particularly those at risk of falls.
Our research into the epidemiology of childhood visual impairment has transformed understanding of the epidemiology, outcomes and impact of childhood visual impairment in the UK. As a result, changes have been made to the Newborn and Infant Physical Examination Programme and the National Vision Screening Programme. Our work has underpinned the development of new quality standards for paediatric ophthalmology services issued by the Royal College of Ophthalmologists. Our studies on congenital cataract have improved the management of this condition nationally. We have involved visually impaired service users and patient groups directly in our research to improve quality of life measures and patient engagement.