Impact: Health and welfare; healthcare guidelines on elective
induction of labour. The research showed that elective induction at time
points from 37 weeks' gestation progressively reduces perinatal mortality.
UK guidelines now recommend routine induction at 39 weeks in mothers
>40 years of age.
Significance: Implementation of the guidelines for mothers >40
years of age is estimated to prevent the stillbirth of 17 babies per year
in the UK.
Beneficiaries: Pregnant women, policy makers and healthcare
Attribution: The work was led by Jane Norman with Sarah Stock at
UoE, in collaboration with NHS Information Scotland.
Reach: UK, Europe, North America. Applies to all pregnant women,
especially those over 40 years of age.
Impact: Health and welfare; public policy; the work led to UK and
international guidelines advising
against progesterone use to prevent preterm birth in twin pregnancy.
Significance: Thousands of women now avoid this unpleasant
procedure annually, with a saving
to the NHS of £25M.
Beneficiaries: Pregnant women, policy-makers, the NHS and
Attribution: The work was initiated by a five-centre UK
collaborative group including UoE. Data
analysis, interpretation and translation into practice were led by Jane
Reach: The data are cited in guidelines and have changed clinical
practice on three continents:
Europe (NICE), North America and Australasia. Applies to 11,000 women
annually in UK alone.