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Bisphenol A and its potential human health effects

Summary of the impact

Professor Tamara Galloway's research has identified for the first time associations between exposure to one of the world's most widely used chemicals, bisphenol A (BPA), and an elevated risk of developing cardiovascular disease (CVD), the leading cause of death globally. Specifically the 25% of individuals with highest urinary BPA levels, compared to the 25% with the lowest levels, have a 1.5-2 fold increased risk of developing CVD. This finding has influenced international policy debate and resulted in restrictions on the use of BPA in food contact materials, and is stimulating industry investment into safer chemical alternatives. Furthermore it has raised public awareness of the associated health risks.

Submitting Institution

University of Exeter

Unit of Assessment

Biological Sciences

Summary Impact Type

Health

Research Subject Area(s)

Medical and Health Sciences: Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services

Bisphenol A and its potential human health effects

Summary of the impact

Research by Professors Tamara Galloway, David Melzer, and Michael Depledge at Exeter identified, for the first time, associations between exposure to the widespread environmental contaminant bisphenol A (BPA) and changing incidences of disease. The research showed that higher exposures to BPA are associated with an increased risk of cardiovascular disease and hormonal changes. The research has influenced policy development worldwide, raised public awareness of environmental chemical health risks, stimulated public debate and critical media analysis, and is stimulating enhanced public, policy-maker and business interest in anthropogenic chemicals in the environment and their implications for human health.

Submitting Institution

University of Exeter

Unit of Assessment

Earth Systems and Environmental Sciences

Summary Impact Type

Health

Research Subject Area(s)

Medical and Health Sciences: Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services

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