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Bisphenol A and its potential human health effects

Summary of the impact

Research by Professors Tamara Galloway, David Melzer, and Michael Depledge at Exeter identified, for the first time, associations between exposure to the widespread environmental contaminant bisphenol A (BPA) and changing incidences of disease. The research showed that higher exposures to BPA are associated with an increased risk of cardiovascular disease and hormonal changes. The research has influenced policy development worldwide, raised public awareness of environmental chemical health risks, stimulated public debate and critical media analysis, and is stimulating enhanced public, policy-maker and business interest in anthropogenic chemicals in the environment and their implications for human health.

Submitting Institution

University of Exeter

Unit of Assessment

Earth Systems and Environmental Sciences

Summary Impact Type

Health

Research Subject Area(s)

Medical and Health Sciences: Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services

The plastics chemical Bisphenol A and its potential human health effects

Summary of the impact

Research by Professors David Melzer and Tamara Galloway on the bioactivity of Bisphenol A (BPA) an oestrogenic chemical widely used in plastics, has influenced public policy on an international scale and led to improvements in human health. They demonstrated that BPA is active in the human body at commonly experienced concentrations and that higher exposures are associated with hormonal imbalance and coronary artery disease. The outcomes have stimulated policy debate and led to a reappraisal of the environmental risks associated with BPA exposure. Regulatory authorities across the world are now committed to reducing BPA residues in food and beverages.

Submitting Institution

University of Exeter

Unit of Assessment

Clinical Medicine

Summary Impact Type

Health

Research Subject Area(s)

Medical and Health Sciences: Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services

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