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Scientific discoveries in skin pigmentation contribute to the development of best-selling skincare products of high commercial value

Summary of the impact

Ground breaking and unique research carried out at the Centre for Skin Sciences at the University of Bradford has led to the realization of commercial opportunities in two very high-value consumer brands. Technologies developed in collaboration with multi-national personal-care and cosmetic companies for the treatment of skin hyper-pigmentation have been launched on the market and have reached thousands of consumers. The first product launched by Alliance-Boots (April 2012) is sold within the UK's premier skincare range (No. 7). Success in Britain led to its launch in the US, Finland and Thailand. A second product within the Diorsnow range has been launched by Parfum Dior — a branch of LVMH Moët Hennessy • Louis Vuitton S.A.

Submitting Institution

University of Bradford

Unit of Assessment

Allied Health Professions, Dentistry, Nursing and Pharmacy

Summary Impact Type

Technological

Research Subject Area(s)

Biological Sciences: Biochemistry and Cell Biology
Medical and Health Sciences: Clinical Sciences

synthetic peptides

Summary of the impact

The Farndale group have identified fragments of collagen, synthesised and assembled in active, triple-helical conformation, for use as ligands to manipulate platelet function. As a result of this work, the fragment Collagen-Related Peptide (CRP) is included in British Committee for Standards in Haematology guidelines as a platelet agonist for the diagnosis of platelet defects. The group has also synthesised triple-helical collagen peptide libraries and used them to map binding of cells or proteins to collagen more widely. The peptides are made and distributed by the Farndale lab, generating income through sales and licencing, and are used internationally by companies and hospitals to develop diagnostics and for high-throughput drug discovery. Prof Farndale also acts as a consultant for companies developing diagnostics.

Submitting Institution

University of Cambridge

Unit of Assessment

Biological Sciences

Summary Impact Type

Technological

Research Subject Area(s)

Biological Sciences: Biochemistry and Cell Biology
Medical and Health Sciences: Cardiorespiratory Medicine and Haematology

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