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Treating stroke consumes 5% of the NHS budget. Government objectives for improving stroke rehabilitation have driven our important advances in aiding recovery of movement and independence. We have developed and evaluated innovative technologies and directly ensured translation into clinical practice and home use. Over 2,500 therapists have received training in functional electrical stimulation (FES) in the UK and abroad. Our research into FES and upper-limb robot therapy has attracted great media attention, as well as international clinical and commercial success. FES is now incorporated into National Institute of Health and Care Excellence (NICE) and Royal College of Physicians (RCP) Stroke Guidelines. We have demonstrated successful adoption of technologies in practice (the main UK commercial provider reports 16,000 sales of FES devices), and we have published evidence for their continued use.
University of Salford researchers have transferred knowledge from research in the foot health devices sector into products and services in commercial and clinical settings, supporting a £100 billion global healthcare equipment and supplies industry, contributing to economies and to quality of life on a daily basis for those with foot and lower limb health problems, world-wide. The benefiting partners are part of global businesses and public and private sector clinical services and researchers have pioneered the connection of research to commercial foot health contexts on a unique scale:
Functional electrical stimulation (FES) to the ankle dorsi-flexors is an assistive technology that aims to counter foot drop, a common symptom in people with neurological impairment. Our research has facilitated a better understanding of the clinical potential of FES as a means to enhance walking capability and ultimately the quality of life of people with gait abnormalities associated with "dropped foot". The production and dissemination of this research has directly had an impacted on local NHS clinical treatment practice and NHS clinical service evaluation/re-design in support of self-managed care of people with long-term conditions such as Cerebral Palsy, Stroke, and Multiple Sclerosis.
The key driver for this research is to provide clinicians with robust tools that they can use to evaluate, treat and therefore improve the clinical outcome in their patients. Our research has assisted the development of the evidence base of many clinical treatments and assessment tools. This has led to the design and development of new rehabilitation products and medical devices in partnership with both large companies and small to medium sized enterprises. The core impact of this work has been improvements in patient care and quality of life by improving the efficacy and effectiveness in these areas with a particular focus on the advancement of conservative management and lower limb rehabilitation.
Research carried out by the SESRC has resulted in a new category of health and wellness footwear which has been commercialised by FitFlop Ltd.
Since 2008, the Company has:
The University of Glasgow's Centre for Rehabilitation Engineering (CRE) has developed strategies and products that have influenced clinical practice in Spinal Cord Injury (SCI) worldwide. The CRE refined the concept of using Functional Electrical Stimulation (FES) for cycling and abdominal stimulation and defined its benefits to patients by establishing the nature of the medical benefits of the technology.
Working with clinical partners in the Southern General Hospital and Hasomed GmbH, the CRE co-developed FES products that are now used routinely in clinical rehabilitation. Hasomed sell ~500 units p.a. across the world, for use at home, in fitness centres and in SCI clinics to maintain health and wellbeing, thereby reducing patient morbidity and increasing their life expectancy.
Neuro-feedback, utilising a Brain Computer Interface for the treatment of pain associated with SCI, has also been developed into a clinical reality and a limited clinical trial has now shown its efficacy.
Glasgow Caledonian University researchers have dramatically changed the manufacture of custom ankle-foot and foot orthoses through additive manufacturing (3D printing) combined with improved design personalisation. The research has beneficially impacted on health and well-being as new 3D printed orthoses have been designed and trialled with patients with positive outcomes reported. Moreover, European SME companies in the orthotic design and manufacture sector have benefitted through the commercialisation of new orthotic products and computer-based design optimisation software. The research has also led to raised global awareness of the capabilities of additive manufacturing for the orthotic sector and beneficially influenced manufacturing research and development funding at the European policy level.
Through the introduction of innovative design approaches, processes tools and methods into the research of complex healthcare issues, a range of individuals — including members of professional groups, e.g., in nutrition management and physical rehabilitation, clinical trials managers, healthcare professionals and patients (involved, e.g., in random controlled trials), are now able to consider and use tools and approaches that they did not use previously. These, policy-makers, leads in research councils, charities, and members of lay user representative groups have seen, through demonstrations, national and international presentations and professional publications, advantages of these innovative tools and approaches that enable more patient-centred treatment and enhanced patient-professional relationships.
A team of biomedical engineers at UCL has developed a non-invasive growing implant that improves the health and quality of life of young patients who have suffered from certain bone cancers. The prosthesis avoids the costly and invasive surgical interventions of previous treatment. Instead, the prosthesis can be lengthened in a quick and pain-free procedure conducted at an outpatient clinic. As a result, it reduces the costs of bone reconstruction and growing by around £19,000 per patient, as well as reducing the risk of infection and subsequent treatment. Since 2008, more than 400 devices have been sold; in addition to the cost savings indicated above these devices have generated more than £6 million income for UCL spin-out company Stanmore Implants Ltd, which was sold for £10 million in 2008.
Research carried out by the SESRC has resulted in the development of three novel devices that improve foot and lower limb circulation. These have been commercialised by Actegy Health Ltd.
Since 2008, impact arising from this research includes,