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MMU Research Impact On Combating Musculo-skeletal Disuse In Older People.

Summary of the impact

Manchester Metropolitan University's (MMU's) novel research on the musculoskeletal adaptations to resistance training has directly informed what has been called the "gold-standard" for exercise, physical activity and rehabilitation guidelines for older adults published in the USA, as well as the UK Department of Health's guidelines on physical activity and exercise for older adults. MMU's musculo-skeletal research has led to commercial impacts as it has directly informed the design, and modifications to the design of `Technogym' (an international exercise equipment manufacturer) and vibration training devices. Clinical impacts have been realised through the contribution of musculoskeletal research into rehabilitation programmes for children with muscle weakness across Europe. And finally, MMU's research has also raised awareness of, and informed local Government decision-making and policy on, ageing and musculoskeletal deterioration.

Submitting Institution

Manchester Metropolitan University

Unit of Assessment

Allied Health Professions, Dentistry, Nursing and Pharmacy

Summary Impact Type

Societal

Research Subject Area(s)

Medical and Health Sciences: Clinical Sciences, Human Movement and Sports Science, Neurosciences

Commercialisation of Creatine and Carnitine for Sports Nutritional Supplements

Summary of the impact

An international patent emanating from research from Professor Paul Greenhaff's laboratory and owned by the University of Nottingham (UoN) was purchased by MuscleTech Inc. in 2001 (along with provision of £750k research funding), and used to underpin their highly successful creatine based sports supplement, CellTech. The patent has since been used in [text removed for publication] products creating sales worth $[text removed for publication] million (US) since 2010. A further international patent from the same laboratory based on research on carnitine as a sports supplement has to date been accepted in Australia and Canada and used by the Olympic Team GB in 2012. Negotiations between the UoN and a global company regarding the licencing of this technology are at an advanced stage.

Submitting Institution

University of Nottingham

Unit of Assessment

Biological Sciences

Summary Impact Type

Technological

Research Subject Area(s)

Medical and Health Sciences: Clinical Sciences, Human Movement and Sports Science, Medical Physiology

Development and commercialisation of a range of medical devices that stimulate improved blood circulation and improve general health.

Summary of the impact

Research carried out by the SESRC has resulted in the development of three novel devices that improve foot and lower limb circulation. These have been commercialised by Actegy Health Ltd.

Since 2008, impact arising from this research includes,

  • successful product efficacy trials satisfying Advertising Standards Authority requirements;
  • filing of three patent applications;
  • generation of total revenues of £53M of which in 2012 two thirds were overseas (£16.3M);
  • created 22 direct jobs with significantly more indirect jobs in manufacturing, logistics and marketing;
  • a Red Dot Good Design international award in 2012;
  • recognition of Actegy Ltd as a Sunday Times fast track 100 company in both 2010(4th) and 2011(17th).

Submitting Institution

London South Bank University

Unit of Assessment

Sport and Exercise Sciences, Leisure and Tourism

Summary Impact Type

Technological

Research Subject Area(s)

Medical and Health Sciences: Cardiorespiratory Medicine and Haematology, Neurosciences

From laboratory to Amazon.com and the NHS – How breathing training joined the mainstream

Summary of the impact

Research by Alison McConnell and colleagues has underpinned the creation of a new category of exercise training and rehabilitation; "breathing training" improves exercise tolerance and reduces perceived exertion. McConnell invented the market-leading POWERbreathe® breathing trainer, and since joining Brunel (2000), has led further new product developments via Knowledge Transfer Partnerships (KTP) and consultancy. Research by McConnell and her team underpins marketing by POWERbreathe® and several "copycat" products serving UK and overseas markets. Impacts include: 1. physiological benefits to individual users globally, from elite athletes to patients; and 2. commercial benefits to POWERbreathe International Ltd., its supply chain, and to new international businesses serving the breathing training market created by POWERbreathe®.

Submitting Institution

Brunel University

Unit of Assessment

Sport and Exercise Sciences, Leisure and Tourism

Summary Impact Type

Technological

Research Subject Area(s)

Medical and Health Sciences: Human Movement and Sports Science

The development of column-based mid-sole (‘Microwobbleboard’™) technology, leading to the creation of FitFlop Ltd, a global footwear brand.

Summary of the impact

Research carried out by the SESRC has resulted in a new category of health and wellness footwear which has been commercialised by FitFlop Ltd.

Since 2008, the Company has:

  • Achieved sales of over 17million pairs of FitFlop™ footwear, generating revenues of $350million;
  • Increased its worldwide workforce from 17 (in 2008) to 160 (2012);
  • Expanded its operations into 52 countries with sales operations in the UK, France, Italy, Spain and the USA;
  • Grown from a single to a multi-product footwear manufacturing and retail brand;
  • Received the Seal of Acceptance from the American Podiatric Medical Association (APMA), and won business awards in 2011 and 2012.

Submitting Institution

London South Bank University

Unit of Assessment

Sport and Exercise Sciences, Leisure and Tourism

Summary Impact Type

Technological

Research Subject Area(s)

Medical and Health Sciences: Clinical Sciences, Human Movement and Sports Science, Neurosciences

A new treatment for equine and human tendon injuries

Summary of the impact

Fundamental and applied research at RVC has led to introduction of stem cell therapy supporting equine tendon regeneration, advancing equine clinical practice internationally. A resultant spin-out company has delivered revenue-generating veterinary clinical services internationally and is now developing new human treatments. The therapy offers improved health and welfare, particularly in racing, as treated horses are less likely to re-injure in comparison with those managed conventionally, and consequently less likely to be culled due to premature termination of their competitive careers. The acceptance by the Medicines and Healthcare products Regulatory Agency that the equine treatment data provide validation for a phase II human clinical trial without further preclinical studies represents a rare and significant outcome for veterinary research.

Submitting Institution

Royal Veterinary College

Unit of Assessment

Agriculture, Veterinary and Food Science

Summary Impact Type

Technological

Research Subject Area(s)

Medical and Health Sciences: Clinical Sciences, Neurosciences

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