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Footrot (FR) causes 90% of lameness in sheep. FR reduces productivity and lowers sheep welfare. Research at the University of Warwick, initiated in 1999 and still active, has led to the development of a novel management strategy for footrot in sheep: prompt antibiotic treatment (PAT) - sheep treated with intramuscular and topical antibiotics within three days of becoming lame with FR. This has resulted in a reduction in the overall prevalence of lameness in sheep flocks in England from 10% (2004) to 5% (2011) and 3% (2013). In 2011, evidence from research at Warwick on PAT was used by the Farm Animal Welfare Council of Great Britain to support their statement that it was feasible to reduce the prevalence of lameness in the national flock from 10% to 2% by 2021. From 2005 onwards, PAT has been disseminated to 50,000 sheep farmers through knowledge transfer (KT) by EBLEX, the levy body for sheep farmers in England using booklets, CDs and more than 100 on-farm events. More than 50% of farmers who had attended an EBLEX KT meeting on lameness stated that they had changed their management of lameness as a result of new information from the event. The Sheep Veterinary Society in the UK has adopted PAT as the recognised management approach for FR and a leading sheep vet in Germany has written a book promoting PAT. The work has been presented in Europe as part of Animal Welfare Research in an Enlarged Europe (AWARE), an EU-funded project educating all countries in the enlarged EU zone on animal welfare (http://tinyurl.com/o6onaxd). In 2012, the lead Warwick researcher Professor Green was awarded the Royal Agricultural Society of England medal specifically for `impact to the sheep farming community in reducing footrot in sheep'.
Hundreds of millions of laying hens in the European Community are now kept in enriched cages with significantly more space than conventional battery cages and with specific provision for nesting, scratching and perching. Research undertaken at Bristol University provided much of the evidence base for the full implementation of the relevant European directive in January 2012; the prohibition of the conventional battery cage and the introduction of a superior, scientifically researched alternative. This has had a dramatic impact on husbandry standards and the welfare of laying hens. With Bristol's involvement, similar progress has also been made in countries beyond Europe.
In the UK, one in seven dairy calves dies annually during rearing. Herd profitability is reduced further by calfhood disease and suboptimal growth rates, delaying age at first calving and reducing milk output. Professor Claire Wathes's longstanding scientific interests in dairy cattle reproduction and development have led to a broader farming industry appreciation of this issue, and to new approaches that address the economic loss and welfare issue it represents. Her results are now incorporated into professional and practical advice from DairyCo (industry levy board); Defra; farm veterinarians; commercial feed companies; opinion leaders in dairy farming; and the specialist farming media.
The use of non-steroidal anti-inflammatory drugs (NSAIDs) for their pain-relieving properties in cattle medicine has lagged behind that of other species (e.g. companion animals) where analgesic use is now routine. University of Nottingham (UoN) research exploring the attitudes of vets and farmers to the use of NSAIDs in cattle, and subsequent marketing by Boehringer Ingelheim, a multinational pharmaceutical company, has led to a substantial increase in analgesic use. UoN research increased sales for Boehringer Ingelheim and almost doubled the UK market value of NSAIDs for use in cattle. With administration of up to 2 million additional doses per year, the research had clear benefits for animal welfare.
Research conducted at the University of Bristol between 2002 and 2006 directly influenced a significant commercial decision about use of a food additive to aid appetite control, which protected consumers from an ineffective product. Concerns about increasing levels of obesity worldwide and the toll this takes not only on human health but on health care costs, have led to the development of food ingredients that satisfy hunger for longer (enhance satiety). One such major new ingredient, Fabuless, which is owned by DSM (Dutch State Mines), a leading global manufacturer of food ingredients, was being considered by Unilever for inclusion in its range of diet foods. DSM and Unilever contacted Professor Peter Rogers, who is known for his novel methods for the experimental study of appetite control, to test the effectiveness of Fabuless. Rogers demonstrated no satiety effect of Fabuless when consumed in realistic products, which caused Unilever to abandon Fabuless as a potential food ingredient in 2009. Publication of the research also meant that other food manufacturing companies and regulatory authorities were informed about the ineffectiveness of Fabuless.
The University of Nottingham (UoN) has been at the forefront of research into intramammary infections during the non-lactating (dry) period in dairy herds. This research, disseminated through presentations to key stakeholders and veterinary textbooks, has changed clinical and farmer practices as evidenced by international disease/welfare reports, national control programmes and increased use of non-antibiotic teat sealants. The work has culminated in the launch of a novel software tool that uses the research findings to provide a farm-specific decision aid, which benefits the business activities of dairy farmers and improves animal health and welfare.
Fertility of dairy cows has been in decline since the 1970's and this has threatened sustainability of the dairy industry worldwide. Research led by Nottingham University (UoN) identified key drivers of fertility and provided genetic and nutritional tools for the industry, to help combat the decline. The genetic tool was the UK Fertility Index, which is used universally by breeders for national and international bull selection. The nutritional tool, which is widely applied by international feed companies, used the concept that nutritional manipulation of insulin enhances fertility. Evidence shows that use of these tools between 2008 and 2013 has reversed the decline, and fertility is being restored. This has brought commercial benefits for breeding companies, cattle food producers and farmers and had a positive impact upon animal welfare.
Impact: Economic / animal health and welfare / environment: Improved profitability and sustainability of the UK dairy industry.
Significance: The use of the Profitable Lifetime Index (£PLI) increased the profitability of the dairy sector by an estimated £634M in 2008-2013 and reduced the greenhouse gas emissions from the sector by an estimated 8.4%.
Beneficiaries: Dairy producers, breeding companies, general public/environment, dairy cattle welfare and health.
Attribution: Drs Wall, Mrode (SRUC), and Brotherstone (UoE), Profs. Coffey, Simm, Stott, Veerkamp, Oldham (SRUC), and Woolliams (UoE/Roslin)
Reach: UK dairy industry. Tools developed, such as the routine recording of body condition score, and using these data in national genetic evaluations, have been widely adopted internationally, including in major dairy genetics exporting countries such as the USA, Canada, the Netherlands and New Zealand.
The wheat-breeding industry, including some of the largest plant breeders and seed-development companies in the world, has benefited from decreased production costs and increased productivity as a result of research led by the University of Bristol and carried out between 2009 and 2011. The Bristol researchers developed the tools necessary to differentiate point mutations in the complex DNA structure of wheat. This was a critical step in wheat genotyping and led to the public release of 95% of the wheat genome in 2010 and the development, by Bristol, of a cheap, easy-to-use assay for industry. These advances were quickly embraced by industrial wheat breeders aiming to deliver new varieties of wheat with improved yields and desirable traits such as disease resistance. Limagrain, the world's fifth-largest producer of field seeds (including wheat) with €595 million in sales of seeds, realised a ten-fold reduction in costs and a ten-fold increase in throughputs in their breeding laboratory. With the wheat-seed business worth over £16 million annually in the UK and over £1.8 billion globally, the new genotyping tools generated by Bristol have had, and continue to have, a major impact on the wheat industry and its ability to respond to the challenges of climate change and population growth.
Impact on health and welfare: The health and welfare of laying hens has been improved by the EU-wide ban on the use of small, barren battery cages, enabled by UoE research on the relationship between cage design and welfare.
Impact on public policy and services: The EU banned conventional battery cages for laying hens through a directive that came into effect on 1st January 2012. New Zealand followed with its own ban in 2012.
Impact on production: Farmers have changed from housing laying hens in battery cages to using more welfare-friendly furnished cages or free-range systems.
Impact on commerce: In the UK, over £400M has been spent to meet the standards laid down by the EU directive.
Beneficiaries: Laying hens in Europe and New Zealand; farmers who use furnished cages as an economically efficient alternative to free-range.
Significance and Reach: The improved welfare of over 1.3 billion laying hens in Europe and New Zealand.
Attribution: All research was led by Dr Michael Appleby, University of Edinburgh (1984-2001), with collaborators at the Roslin Institute (now UoE), Uppsala and Bristol.