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Research at the University of Cambridge, Department of Physics on sensitive techniques for measurements of magnetic and electrical properties of materials led to the selection of Dr Michael Sutherland as an expert witness in a series of major police investigations involving fraudulent bomb detecting equipment. Scientific evidence Dr Sutherland presented in court was key in securing guilty verdicts, leading to the breakup in 2013 of several international fraud rings with combined revenue in excess of £70 million. This criminal activity had caused significant damage to the reputation of the UK in Iraq and elsewhere.
Impact: Economic and societal The Millimetre Wave and Electron Paramagnetic Resonance (EPR) group has developed internation-ally award-winning instrumentation, and associated components that have been produced commercially by Thomas Keating Ltd. They have also led a pio-neering public understanding programme (PUP).
Significance: Thomas Keating have developed a range of new product lines serving > 20 international customers including [text removed for publication] of recent orders. The PUP has reached ~82 000 at-tendees.
Reach: Systems have been sold internationally and PUP has developed into specific exhibitions at a range of science centres.
Attribution: The work has been led by PHYESTA Researcher Dr Graham Smith
Heat capacity is the measurable physical quantity that specifies the amount of heat required to change the temperature of an object or body by a given amount and is an important quantity to establish in any application that requires knowledge of the thermal response of a material. It is quite usual in the development of new materials that the volume of material available in single crystalline form is limited, and the ability to measure small samples sensitively has particular importance for this reason. We claim a dominant influence on the design of an ultrasensitive heat capacity microcalorimeter that is now sold by the UK company Cryogenic Ltd as a heat capacity option for their cryogenic measurement systems. The microcalorimeter makes it possible to measure ultra-small samples, particularly magnetic samples that are invisible to other commercial probes. Research was carried out within Imperial's Physics Department in 2003-04 to develop the instrumentation; the design was published in 2005 after which it transferred to UK company Cryogenic Ltd. In the past three years the approximate total sales of the heat capacity option at Cryogenics amount to £500K, as a valuable component of a physical properties measurement system with a total sale value in the region of £2M [section 5, source E].
XMaS is a dedicated materials science beamline at the European Synchrotron Radiation Facility (ESRF). It develops and disseminates novel instrumentation and sample environments that allow new experiments which support emerging technologies. By commercialising the intellectual property through licenses to companies economic impact is derived directly. Further economic impact is facilitated through knowledge transfer by trained people and expertise in new processes, which enhances the capability, capacity and efficiency of other central facilities. Public interest and awareness are engendered through individual research projects being highlighted in the media and through people's skills and experience being utilised in a broad range of sectors.
Groundbreaking UCL research and development of magnetic nanoparticles for biomedical applications led to the introduction in 2012 of the world's first licensed nanoparticulate injectable medical device, the Sienna+ tracer, and its associated detection system, the SentiMag. A UCL spinout company, Endomagnetics Ltd., has introduced this new technology to better diagnose and treat cancer without the need for invasive surgery. The system uses magnetic materials, rather than radioisotopes, to locate the sentinel lymph nodes that are the key indicators of the spread of cancer away from the primary tumour site. As well as improving patient outcomes, the system considerably improves hospital workflow and efficiency since, unlike radioisotopes, the injectable magnetic tracer (Sienna+) is readily available and requires no special handling
A software package called CPO has been developed that simulates the motion of charged particles in electromagnetic fields. More than 200 benchmark tests have established CPO as the gold standard in low-energy charged-particle optics. A spin-off company was formed to market CPO, [text removed for publication]
Durham Chemistry has a long history of research in cutting edge crystallographic methods and innovative instrument design which has led to the commercialisation of scientific apparatus and software with significant sales value. Durham-developed apparatus and crystallographic software are used globally by both industry and academia. Autochem2, for example, is sold exclusively to Agilent via the spin-out company OlexSys, and hundreds of researchers rely on Durham's contributions to the Topas software pacakge. Crystallographic research for pharmaceutical and other companies, research-based consultancy, commercial analytical services and provision of international PhD+ level training schools have led to further significant impact.