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This UoA has developed the largest independent simulation laboratory in the world for pre-clinical evaluation of the wear of artificial joints, which has been used to develop and commercialise novel pre-clinical simulation systems for joint replacements, in partnership with Simulation Solutions Ltd. Simulation Solutions Ltd is now the market leader of joint simulation systems outside North America.
We have also co-developed lower wearing ceramic-on-ceramic and ceramic-on-metal bearings for hip joints, and have worked with DePuy Orthopaedics Inc to define lower wearing tribological solutions for polyethylene knees. This work has benefited hundreds of thousands of patients worldwide during the REF period.
University of Huddersfield research into engine technologies has resulted in a major new partnership with the UK arm of engineering multinational BorgWarner, leading to the company increasing R&D capabilities in the UK. This collaboration, funded partly by parent company BorgWarner US and partly by the government's Regional Growth Fund, involves multi-million-pound investment, as well as significant job creation and safeguarding. It was a key factor in the company securing a substantial contract with Jaguar Land Rover, whose decision was informed by the University's capacity to help BorgWarner further its R&D activities and upskill its workforce for the benefit of the UK automotive supply chain and the local and national economy.
Ehiasarian and Hovsepian of the Materials and Engineering Research Institute (MERI) have achieved significant economic impact through industrial uptake of their innovations in High Power Impulse Magnetron Sputtering (HIPIMS). Exploiting these innovations, HIPIMS treatments have been used by manufacturers to enhance the surface properties of millions of pounds worth of products. Applications include industrial blades, components within jet turbines, replacement hip joints, metallised semiconductor wafers and satellite cryo-coolers. Patents based on Ehiasarian and Hovsepian's research have achieved commercial success. In the REF impact period, HIPIMS machines equipped to deliver MERI''s HIPIMS surface pre-treatment have achieved sales of over £5m, and income generated through SHU's HIPIMS-related licences has totalled £403,270. In 2010 Ehiasarian's group established the Joint Sheffield Hallam University-Fraunhofer IST HIPIMS Research Centre, the first such Centre in the UK. This has broadened the industrial uptake of MERI's HIPIMS technologies and stimulated a network of sub-system providers.
The nanobiotechnology research group at the University of Kent (Bruce et al.) has pioneered the ability to control, manipulate and commercially process magnetite nanoparticles. Two spinout companies, EryDel and Dietheva have been formed, with a €6 million venture capital grant, as a direct result of the Kent-led research. EryDel (in collaboration with Philips Healthcare) are exploiting the materials worldwide for drug delivery (Erydex), with US and European approval for Orphan drug designation given in 2013 for genetic diseases, and Diatheva are marketing the technology for forensic diagnostic kits. The predicted five-year revenue is €35 million with a potential market of €17 billion.
Research into distributed optical fibre sensing undertaken at the Optoelectronics Research Centre (ORC) at the University of Southampton has had profound economic and environmental impact within the oil and gas industries in both extraction efficiency from existing reservoirs and improved safety performance and operation of three companies: Optasense, Stingray Geophysical and Schlumberger. Each of these companies have established highly competitive positions in the worldwide optical sensor market and collectively employ more than 160 people in the south of England, in their distributed sensing programmes having benefitted from the adoption of this new technology that contributes to the management of environmental risks and hazards.
The underpinning research has led to a methodology for cost-effective monitoring systems to interpret complex and emergent conditions in real-world applications. There are ten different organisations utilising the technology, benefitting the UK economy and health care provision, both nationally and internationally. These include MAST Group Ltd, Electricity North West Ltd, TMMHRC (India) and the Milestones Trust (Bristol). The impacts are (i) Economic: improving business capabilities and UK company profit margins (ii) Societal: benefiting health sector organisations in India and in the UK through improved diagnosis and care for the elderly and vulnerable; and (iii) Environmental: reducing waste and carbon footprint.
Two leading manufacturers of clothing for outdoor activities ([text removed for publication]) have produced a new range of functional clothing based on research at Ulster on wearable technologies for the active ageing. The new age-appropriate outdoor garments incorporate wearable technologies that enable self-monitoring of physiological parameters (heart rate, respiration rate) and activity levels (step-counts, distance walked) with optimal placement of sensors to improve signal-to-noise ratio. Additionally, [text removed for publication], a company producing [text removed for publication], have used feedback from Ulster's research evaluations to design a new range of [text removed for publication] that are incorporated into the garments, achieving increased levels of usability by elderly people.
Nature's Raincoats is a physical exhibition and a website providing easily accessible information and resources. These entities have had extensive use within the public understanding of superhydrophobic surfaces (extremely repellent to water), including The Royal Society Summer Science Exhibition, Cheltenham Science Festival, The Big Bang Fair, British Science Festival and Techfest (India) — reaching thousands of people in the UK and overseas. As well as impacting on improved public awareness, the research informed website provides a direct route to research expertise for companies within the UK and internationally and extends good practice of working with industry e.g. Rolls Royce.
Aston's fibre Bragg grating research on optical sensing has had a global commercial impact, in particular the development of low-cost fibre FBG sensor interrogation methods. The work has been carried out with a diverse range of companies (including BAE Systems, Airbus, Insensys, Schlumberger) working across different sectors including oil and gas aerospace and marine. Specific impacts include the acquisition of 70% of the stock of Insensys Wind for US$15.7 million by Moog in 2009 and continuing employment by Smart Fibres, Moog Insensys and Astasense.
Each year an estimated 1,324,000 artificial knee joints (total knee replacements — TKR) are implanted worldwide; an estimated third of these utilise an implant manufactured by DePuy International. Underlying computer-based research performed by the Bioengineering Sciences Research Group has played a central role during the development of a new design of TKR for DePuy. The design programme, the biggest in DePuy's history, had a budget in excess of US$10 million and aimed to replace the existing TKR system, which had annual sales of approximately US$100 million.
Between 2007-2010, DePuy adopted the computational techniques developed by the group as screening tools to (i) assess polyethylene wear and (ii) account for the effects of surgical variability during the early design phases. DePuy states "This research allowed us to choose the most robust solution when proceeding to mechanical testing and saved years in the design cycle. Patients also benefit from increased confidence in an implant that is able to withstand the rigors of use".