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Research by Professor Gary Williamson and researchers at the University of Leeds (UoL) has revealed new pathways of polyphenol absorption and metabolism in humans, including the effect of gut microflora on the bioavailability of these natural compounds found in coffee, having major impact on commerce. Output has provided the scientific evidence to support Nestlé's post-launch marketing for its Green Blend coffee. The UoL research supports Green Blend's key positioning as a "functional" coffee with health benefits because it delivers high levels of antioxidants to the body. The brand has estimated global sales of hundreds of millions of pounds per year.
Research conducted at the University of Bristol between 2002 and 2006 directly influenced a significant commercial decision about use of a food additive to aid appetite control, which protected consumers from an ineffective product. Concerns about increasing levels of obesity worldwide and the toll this takes not only on human health but on health care costs, have led to the development of food ingredients that satisfy hunger for longer (enhance satiety). One such major new ingredient, Fabuless, which is owned by DSM (Dutch State Mines), a leading global manufacturer of food ingredients, was being considered by Unilever for inclusion in its range of diet foods. DSM and Unilever contacted Professor Peter Rogers, who is known for his novel methods for the experimental study of appetite control, to test the effectiveness of Fabuless. Rogers demonstrated no satiety effect of Fabuless when consumed in realistic products, which caused Unilever to abandon Fabuless as a potential food ingredient in 2009. Publication of the research also meant that other food manufacturing companies and regulatory authorities were informed about the ineffectiveness of Fabuless.
Imperial College research on the gut hormone, oxyntomodulin, showed it caused considerable weight loss in man. A powerful long acting analogue suitable for daily human administration (TKS1225) was developed. This was licensed by Imperial to a spinout, Thiakis Ltd, for successful human toxicity testing and then sold to Wyeth for $30 million initially and $120 million on meeting milestones. Wyeth Pharmaceuticals and the full legal agreement was subsequently acquired and developed by Pfizer in 2009.
Researchers at the Scottish Universities Environmental Research Centre (SUERC, University of Glasgow) were the first to develop methods and equipment for screening foodstuffs for irradiation. Their work led to new UK and European standards (BS EN 1788 and BS EN 13751) which provide protection and reassurance to consumers. Professor David Sanderson's laboratory is recognised as the world-leader in the detection of food irradiation. The laboratory is also the only establishment to develop, design and sell photostimulated luminescence (PSL) systems to detect irradiated food. Since 2008 134 laboratories worldwide have taken up these UK-manufactured PSL systems to prevent irradiated ingredients from entering the food manufacturing chain.
One solution proposed to contribute to the resolution of the current UK obesity crisis has been to provide clear, visible and easily understood nutritional information to help consumers make informed decisions when purchasing food. Newcastle research provided two insights: first that consumers found it hard to interpret multiple versions of nutritional labels, and secondly that the label with the highest overall comprehension included traffic light colouring, Guideline Daily Amounts and the words "low", "med" and "high" to aid decision making. This information was used by the Department of Health in their approval of a new, consistent food labelling in June 2013. This system has now been adopted by major manufacturers including MARS, Nestlé UK, PepsiCo UK and Premier Foods, and retailers including Sainsbury's, Tesco, ASDA, Morrisons, The Co-operative Food and Waitrose.
Research at the University of Reading into the origin of acrylamide, a neurotoxin and probable human carcinogen, in cooked cereal and potato products has provided crucial information for the food industry and government agencies. This has enabled important mitigation strategies to be developed. When acrylamide was unexpectedly discovered in food in 2002, there was no explanation for its origin. Pioneering research at Reading showed that it was formed during heating from naturally-occurring sugars and the amino acid asparagine. Because of this knowledge it was then possible to investigate factors affecting acrylamide formation and develop methods of mitigation. Subsequently investigations were undertaken worldwide, including work at Reading, to minimise the problem.
A 14 month research project funded by the Food Standards Agency (FSA) has informed national policy on allergens and food labelling, EU negotiations by DEFRA on Food Information Regulation and Food Standards Agency advice to industry. The project involved the development of a novel method for eliciting consumer views about food labels, the details of which have been communicated by the FSA to relevant government departments. The results of the project have been presented to FSA, at industry events, within academia and allergy charities, while references to the project have been widely circulated on social media and appear on policy and industry websites.
The University of Nottingham (UoN) has developed two novel food-allowed additives based upon xanthan gum. The generation of these structurally modified forms allow xanthan to be used more efficiently in food manufacturing applications and provide nutritional and health benefits. The invention of the new xanthans benefits the global food industry by facilitating new product development and formulation.
Bangor research has significantly affected vegetable sourcing and distribution policies and practice of major fresh producers and UK supermarkets. Using a novel carbon footprinting model that incorporates all components of the production chain, the research demonstrated that footprints of vegetables vary with season, origin, production processes, transport and storage. The application of this model by industry partners has resulted in measures by food producers, suppliers and supermarkets to reduce carbon footprints, providing direct economic and environmental benefits through both waste reduction and technology implementation. Furthermore, the findings have impacted on sustainability policy development by the World Bank, international NGOs and Welsh Government, and influenced consumer awareness and debate on the environmental impact of food.
Our research has led to a change in DoH guidelines on maternal consumption of peanut during pregnancy/breastfeeding.
Guidelines until 2009 advocated the avoidance of peanut in allergic families. However evidence base for this advice was poor and the advice was adopted by families regardless of their allergy status leading to significant constraints on their lifestyles. Our research revealed that peanut allergy is not associated with maternal peanut consumption, and that there was no need for pregnant women to avoid peanut during pregnancy. On the basis of our research DoH concluded that previous guidance was inappropriate and it was thus withdrawn.