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The Centre for Econics and Ecosystem Management is the product of six years of international collaborative research and sector-based consultancy between Writtle College and Eberswalde University for Sustainable Development (Germany). Activities at the Centre include developing a core body of internationally recognised research in the fields of non-equilibrium thermodynamics, complex systems science and adaptive management, and using the research to work with conservation organisations around the World to resolve significant environmental problems. Our sponsors include GIZ, Germany and WWF Germany, and our operations extend from Central America to the Ukraine, Russia, South Eastern Europe, China and Korea.
Collaborative research between Durham Physics and Industry showed that a serendipitously discovered new material had unique, pressure sensitive conduction properties which were derived from quantum tunnelling. This research, published in 2005, is cited as one of the top 25 papers in that Journal for that year. Peratech was set up to commercialise this material for applications including switches and mobile phones as the pressure sensitivity gives a new dimension to scale the response. This company now employs 25 people, has an annual turnover of £3M and won the 2012 Queens award for Enterprise in the innovation category.
Chemtrix Ltd. was established in February 2006 as a 50-50 joint venture between the University of Hull and Lionix Ltd. In 2008 the company attracted investment from Limburg Ventures BV, Panthera, Technostartersfund, Microfix BV and Hugo Delissen (€2 million) that led to the creation of Chemtrix BV. In 2009 the Company launched Chemtrix USA and a second investment round followed with investors Particon BV. In 2012 ESK Ceramics GmbH & Co. KG, acquired a minority interest (30%) in Chemtrix BV based on a valuation of €5.3 million.
The three products developed and marketed by Chemtix, Labtrix®, KiloFlow® and Plantrix®, are differentiated from competitor products as they offer `scalable flow chemistry', such that optimised reaction conditions can be easily scaled from R&D to production. In addition to the employees and investors in Chemtrix the main non-academic beneficiaries of the research have been industrial customers such as Janssen Pharmaceutica NV, Edward Air Force Base, Iolitec GmbH and DSM.
Pioneering research at Essex developed an innovative mathematical method for determining the chlorophyll fluorescence parameter Fo', as well as novel LED lighting technology and a multi-plant imaging system. This instrument is marketed by Technologica. Originally an Essex spinout, the company has sold 42 units across Europe, Asia and South America since 2006, recording its highest ever profits over the past three years (totalling ~£115k). Essex's mathematical method for determining Fo' is also used by other manufacturers, who have since developed their own imaging systems. This research has helped to establish chlorophyll fluorescence imaging as a mainstream screening tool, now used globally to inform a range of crop production and handling strategies.
Kim's research has had significant impact on global discourse on theology of mission across the world's churches mainly through the World Council of Churches (WCC) and the Edinburgh 2010 project. In particular her research helped to establish the pneumatological framework for mission theology evident in the Common Call of Edinburgh 2010 (6 June 2010) and the new World Council of Churches' statement on mission and evangelism, Together Towards Life (5 September 2012), which may be summarised as `finding out where the Holy Spirit is at work and joining in'.
A model of collaborative research excellence describes the work led by Imperial College on the conservation of the Mazarin Chest. Renowned as one of the finest pieces of Japanese export lacquer in the world, the Mazarin Chest is viewed by over 3 million people per year in London's V&A museum. Its preservation has allowed it to travel and culturally enrich global audiences, most recently at exhibitions in USA and Japan. The research on the solvent effects on the preservation of Asian lacquerware is universally recognized as changing the working practice of conservators and curators and is now well established in the teaching and mentoring of heritage organisations around the world.
The research on the use of single source precursors in quantum dot synthesis undertaken by Professor Paul O'Brien in the Department of Chemistry at Imperial College between 1994 and 1999 resulted in papers and a patent which led to the formation of Nanoco Group PLC, currently a world-leader in the supply of quantum dots (QDs). Quantum dots have applications in backlighting for LCD displays, LED general lighting and thin film solar cells. Nanoco was listed on AIM on the London Stock Exchange in 2009 and by January 2013 Nanoco employed 78 people, had annual revenue of £3 million, and had signed agreements with several major companies in the US and Japan including Dow Chemical, Osram and Tokyo Electron.
Cognitive Stimulation Therapy (CST) is an evidence-based, brief, group therapy for people with mild to moderate dementia. It was developed and evaluated by UCL in collaboration with Bangor University. Our research showed significant benefits in cognition and quality of life plus cost-effectiveness. Cognitive Stimulation for people with mild/moderate dementia of all types is recommended by NICE and is now in widespread use across the UK and the rest of the world in a variety of settings including care homes, hospitals and the community. A recent audit by the Memory Services National Accreditation Programme reported that 66% of UK memory clinics surveyed were using CST.
Impact: Economic. The EaStCHEM spin-out company Deliverics has commercialised biodegradable transfection reagents for both the "research tool" and the "RNAi therapeutics" markets (globally valued at £400M and £4 billion respectively). Beneficiaries are the pharmaceutical and biotechnology sectors, and clinicians. The turnover since 2010/11 is £330k and the company currently has five employees.
Significance: Deliveric's agents out-perfom existing materials in term of efficacy and reduced levels of toxicity. They are not hampered by the immunogenicity, manufacturing issues, and carcinogenicity previously seen for viral vectors used as delivery agents. This presents a wide ranging ability to deliver nucleic acids into cells and tissues for biological applications.
Research; date; attribution: EaStCHEM research (2008) led by Bradley reported a family of non-viral DNA delivery agents that offered a highly-efficient and non-toxic method of delivering siRNA/DNA into mammalian cells and tissues. Development and patenting of this technology led to the spin-out of Deliverics Ltd. in 2010.
Reach: International customer base (20 research groups and 10 companies) including specially appointed distributors in Spain (Albyn Medical), South Korea (CoreSciences), and US (Galen).
Professor Welsh's research focuses on the responsibility of states and international organisations to protect populations from mass atrocities, and argues that effective protection requires preventive action in addition to reactive responses to unfolding crimes. The research has directly informed the UN Secretary-General's 2012 report on the Responsibility to Protect, which shapes how UN member-states interpret their responsibilities, and is contributing to expertise and capacity building in the wider policy community. In recognition of the importance and impact of her research, Professor Welsh was appointed Special Adviser to the United Nations Secretary-General on the Responsibility to Protect (R2P) in July 2013.