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Reduction of unpleasant ambient noise during MRI has been enabled through innovative engineering solutions developed at the Medical Research Council Institute of Hearing Research (MRC IHR). Intellectual property was licensed to Optoacoustics Ltd and the resulting OptoActive™ active noise-cancelling headphones for MRI are the only one of their type commercially available, enabling free conversation between patients and clinicians. The product was formally launched in September 2012 and has worldwide sales including in the USA, Europe, Asia and the Middle East.
Research in materials modelling by the Computational Science and Engineering Group (CSEG) is helping aerospace, defence and transport companies design advanced materials and new manufacturing processes. From lightweight components like aeroengine turbine blades to the control of magnetic fields to stabilise the next generation of International Space Station levitation experiments, CSEG is supporting innovations which have:
In the assessment period, CSEG collaborated closely with leading industries in steel-making (ArcelorMittal, Corus), primary aluminium (Dubal, Rusal, Norsk-Hydro, SAMI) and lightweight structural materials for transport and aerospace (European Space Agency, Rolls-Royce).
Abdominal aortic aneurysm (AAA) is a major cause of death in older men, in the UK and elsewhere. A large UK trial led by the University of Cambridge evaluated the long-term benefits of ultrasound screening for AAA in men aged 65-74 years. This provided the basis for the introduction of a UK national AAA screening programme in men aged 65; this was announced in 2008, initiated in 2009, and achieved full coverage of England in 2013. Similar screening has started in Sweden, New Zealand and in parts of Italy, and is being actively discussed in Denmark, Norway and Finland.
As a result of her outstanding research in Roman history and archaeology, Beard was invited to work with a TV production company to develop two programmes for BBC2. The first was a one-off programme specifically linked to her book Pompeii (2008), the second a series (Meet the Romans, 2011) related to her research on Pompeii and to her research on Roman social history and inscriptions. Recognised as landmark broadcasts (Pompeii gained 3.4 million viewers, the largest audience for a factual BBC2 programme in 2010, and was shortlisted for a BAFTA), both have led to widespread public engagement and (with major overseas sales) to considerable economic and cultural benefit to the UK.
Clare Stanford's group has opened up a new line of research for drug treatment of Attention Deficit Hyperactivity Disorder. Based on this work, UCL Business has been awarded an EU patent for the NK1R `knockout' mouse as an investigative tool and pharmaceutical screen. Cerebricon, a subsidiary of Charles River, has taken an exclusive licence to market this mouse and advertise it on their website. Our studies have also enabled us to identify a new genetic locus in which abnormalities are linked to ADHD in humans, and to identify a new drug candidate for treating ADHD.
This case study describes the reach and significance of research conducted by members of the interdisciplinary Sidney De Haan Research Centre for Arts & Health. The examples below focus on the impact of singing as a health and wellbeing intervention for adults within clinical and non-clinical populations. The research has shown that singing has had a beneficial impact on individuals and influenced fields of professional practice in health and social care in the UK and US, service delivery in the UK, and policy development in the UK through the work of the Royal Society for Public Health.
Language impairment is common in children and, without effective early intervention, presents a risk for educational, social and emotional disturbance. The team used their considerable experience in child language research to produce a novel assessment of child language development — The Reynell Developmental Language Scales 3 (RDLS3) — the first test of child language development to be standardised in the U.K. to assess both understanding and production of language in young children. Use of the test has improved language assessment and diagnosis for children with language impairments and, as such, has enabled health and education professionals to target therapy and monitor the effectiveness of interventions to improve child language development. The test has been widely used in the U.K. and is now also being used widely internationally. Recent research by the team has informed a revised version of the test — The New Reynell Developmental Language Scales (NRDLS). Sales figures of the RDLS3 and the commissioning of the NRDLS are testament to its outstanding reputation and enduring legacy worldwide.
This case study is based on research investigating the nature, challenges and potential of audio-drama, and especially bilingual audio-drama. Specifically, it explored the possibilities for creating bilingual drama for monolingual audiences; the effects of using different recording environments; and the advantages of cross-cultural collaboration.
Impact includes: (i) a growth in the practice and reach of bilingual audio-drama in the radio broadcasting sector, both in the UK and internationally; (ii) the establishment of the radio play as an act of live theatre; and (iii) an increased awareness of the possibilities for collaborative audio-drama production across cultural and linguistic borders.
The project led to improved public access to partner collections via a major website, informed the design of the £10m HLF-funded Birmingham History Galleries of Birmingham Museum and Art Gallery (including innovative multi-touch software), and firmly embedded a culture of cross-sector collaboration with impact in Birmingham, the Midlands, and beyond.
The promotion of innovation adoption in high-tech small firms (HTSFs) has long been a European priority, but despite decades of attention, there is still a dearth of innovative HTSFs and, worryingly low participation levels of HTSFs in European R&D and innovation funding programmes. To capitalise on emerging high-tech markets it is imperative that HTSFs have the capacity to exploit these new opportunities and crucially, to contribute to the development of a modern economy. This multidisciplinary impact case investigates how to encourage the involvement of HTSFs in European funding projects. The impact of this research includes; methods for promoting the adoption of high-tech innovation across Europe and the development of European HTSF innovation and R&D funding policy recommendations that feed into the European Parliament, Horizon 2020 and numerous national and European high-tech associations and influential EC innovation networks.