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Techniques that can produce detailed chemical information rapidly and non-destructively for many forensic applications have been developed by Queen's University Belfast based on Raman analysis. The techniques have been adopted by the Forensic Science laboratory in Northern Ireland (FSNI) to trace the source of seized drugs, identify novel psychoactive substances ("legal highs") and study paint evidence. More than 2000 cases of supply/possession of ecstasy drugs, 947 paint casework samples and 100 'legal highs' have been analysed. Other law enforcement agencies are now adopting the methods developed at Queen's.
In a series of papers published from 1999 on, Aitken (Maxwell Institute) and collaborators applied Bayesian statistics to develop a methodology for the quantification of judicial evidence derived from forensic analyses. They proposed and implemented procedures for (i) determining the optimal size of samples that should be taken from potentially incriminating material (such as drugs seized); and (ii) the estimation of likelihood ratios characterising evidence provided by multivariate hierarchical data (such as the chemical composition of crime-scene samples). Their procedures have been recommended in international guideline documents (including a 2009 publication by the United Nations Office on Drugs and Crime) and have been routinely used by forensic science laboratories worldwide since 2008. The research has therefore had an impact on the administration of justice, leading to a better use of evidence and accompanying judicial and economic benefits. Examples are given from laboratories in Australia, Sweden and The Netherlands.
Research in the UAO has led to major advances in the technique of Atom Probe microanalysis. The UOA pioneered the concept of position sensitive detectors for Atom Probe instruments, generated the first 3D data and built the first prototype instruments. Following a series of patented advances and the formation of a spin-off company (subsequently incorporated into Ametek), research in the UOA has led directly to the sale of 45 Local Electrode Atom Probe (LEAP) instruments since 2008 with a value of $102M. These instruments have been used to provide atomic scale chemical information vital to the design of new commercial alloys and to safety cases for life extension of nuclear power plants.
Durham Chemistry has a long history of research in cutting edge crystallographic methods and innovative instrument design which has led to the commercialisation of scientific apparatus and software with significant sales value. Durham-developed apparatus and crystallographic software are used globally by both industry and academia. Autochem2, for example, is sold exclusively to Agilent via the spin-out company OlexSys, and hundreds of researchers rely on Durham's contributions to the Topas software pacakge. Crystallographic research for pharmaceutical and other companies, research-based consultancy, commercial analytical services and provision of international PhD+ level training schools have led to further significant impact.
Research carried out at the Centre for Forensic Linguistics (CFL) at Aston has achieved the following significant impacts:
Methods to improve control over thermally-induced solid state transformations have been developed in Huddersfield and applied to materials synthesis and materials characterisation. Impact is being felt by catalyst and adsorbent manufacturers, where feedback-controlled thermal and microwave methods allow improved control of morphology, surface area and porosity, and possibly the nature of surface sites. New thermal characterisation methods, some based on these principles, plus calorimetric adsorption, modulated differential calorimetric and high speed thermal methods, are being applied to catalytic/adsorbent materials. The information arising from these studies is bringing economic benefit to manufacturers. The same techniques are also being applied to pyrotechnic materials, in work which has been credited with making a significant contribution to defence research in the UK and overseas.
Novel vapour sorption experimental methods for the characterisation of complex particulate materials have been developed in the Department of Chemical Engineering. This research and expertise resulted in the creation of Surface Measurement Systems Limited (SMS), whose Dynamic Vapour Sorption (DVS) and Inverse Gas Chromatography (IGC) instruments are now found in >500 laboratories around the world. They are recognised standard research and development tools in the global pharmaceutical industry (DIN 66138). SMS has contributed >270 man-years of employment and generated £27M of turnover, whilst SMS instruments have generated over £300M of economic value, over the REF period.
This case study describes the impact of physics research, carried out in the Department of Mathematics and Physics (DMAP), on the small business and social enterprise Ten Green Bottles through the development of specific commercial applications, transfers of technology, and the development of new products. Fundamental research on the atomistic origin of the structural and optical properties of recycled and synthetic coloured glass has provided an opportunity for Ten Green Bottles to gain an economic advantage. The collaboration between DMAP and Ten Green Bottles benefits the enterprise's workforce, whose educational ambitions have been extended through the interaction with DMAP research, and also benefits the local community, whose understanding of physics research has been enhanced through their interaction with Ten Green Bottles.
Sustained research in the field of advanced survey design, advanced analysis of complex survey data and the study of public opinion has enabled Professor Cees van der Eijk to make a unique and vital contribution to the work of the Cabinet Office's Committee on Standards in Public Life (CSPL). As an independent public body that advises government on ethical standards across public life in the UK, CSPL has drawn upon Van der Eijk's methodological innovation in data analysis as well as his systematic research to inform its policy recommendations to government. These recommendations have helped to shape policy on matters of public probity, voter registration, MPs' expenses and political party finance. His research for the CSPL has also influenced other independent organisations and the wider public debate on integrity in public life.
Research at the University of Nottingham (UoN) has generated a deep understanding of how semi-crystalline biopolymers, particularly starches and cellulosics, can be controlled through processing to create products with predictable behaviour and with enhanced functionality, especially for texture creation. This knowledge has been transferred to the food industry and to other manufacturers who use natural materials. Concepts developed by UoN have become the bedrock of understanding for large and small manufacturers, enabling them to reduce waste, adapt recipes allowing for cleaner labels and additive reduction, expand the range and quality of materials they can utilise and attempt novel manufacturing procedures.