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Pre-drill prediction of pore pressure and top seal integrity are fundamental aspects of petroleum exploration; incorrect predictions can result in operational difficulties, dry holes and even blow-outs which can cost the industry billions of pounds. The physical and fluid-flow properties of mud-rich sediments exert a fundamental influence on both pore pressure and top seal integrity. Research in Newcastle has quantified the geological controls on these properties and has resulted in data, practical knowledge, algorithms and software which are now used routinely by major companies (e.g. Anadarko, BG, BHPBilliton, BP, ConocoPhillips, Maersk) as part of their global drilling and prospect risking strategies.
This case study describes impact from the Newcastle-led research project to construct the world's first dedicated single-crystal diffraction synchrotron beamline for chemistry and materials science at Daresbury Laboratory Synchrotron Radiation Source (SRS). The result was an innovative and productive facility that has served as the model for the development of other facilities internationally, especially at Diamond Light Source (UK) and the Advanced Light Source (USA). The original Newcastle University research has helped produce scientists now employed by industry and public service sectors around the world. Major new and beneficial drugs and catalysts have been developed with the aid of the synchrotron beamlines and work conducted at these facilities has been critically important for the advancement of the global chemical and pharmaceutical industries and US Government energy development programmes.
Newcastle research is the driving force behind NewChem, a Newcastle University spin-out company which provides creative molecular design and synthetic/analytical services for the pharmaceutical/chemical industry. During 2008-2013, NewChem assisted Shire, a global pharmaceutical company, in the quest for new drugs for treating a range of therapeutic indications, including pain, cardiovascular disorders, ADHD and Alzheimer's disease. Since 2008, NewChem has provided employment for > 60 FTE's and achieved sales exceeding £1 million per annum.
Newcastle research into improving commercial soil-based greenhouse productivity has led to an increase in profitability (due to higher yields and lower costs) and a significant reduction in the negative environmental impacts of commercial, organic and other soil-based greenhouse crop production systems in Europe (UK, Greece and Crete). Newcastle's research has led to improved profits to UK organic tomato farmers estimated to be up to £100,000/ha/year and has allowed large scale organic greenhouse production to be a viable option to meet the demands of the UK organic market. In Greece increased profits are estimated at €25,000 per ha/year and in Crete the estimated value of reduced soil disease control and pest management is €110,000 per ha/year.
Research during the 1990's at Newcastle University resulted in the development of CANopen (Control Area Network open), a manufacturer independent communication protocol for connecting multiple devices used in industrial systems. It has resulted in opening up the market by providing the platform for a low-cost simplified method of connecting off-the-shelf devices to communicate effectively over a network, benefiting the global economy and inspiring innovation. The significance of the impact is evident by the wide incorporation of the technology in a diverse range of products ranging from health care, automotive, renewable energy, rail and aerospace industries. The reach of the impact is evident by its use in product development by national and international companies and is the de-facto European standard EN 50325-4 (CiA 301).
Research at Newcastle University on formal methods for the design of computing systems has had a major impact on the delivery of new high-dependability products by industry. The methods (VDM and Event-B), to which we have made significant contributions, have been embodied in tools (VDMTools, Overture, Rodin) and applied in industry. The reach of the work extends to industries in Europe (e.g. in the rail sector by Siemens, 2011) and Japan (e.g. in firmware design by Sony, 2008). Significance is seen in reported improvements in defect detection rates of up to a factor of 5 over previous processes and the cost-effectiveness of design processes. The "Mobile FeliCa" chip developed using VDMTools is now incorporated into over 200 million mobile phones worldwide. Our approach to disseminating research has engendered lively international and online end-user communities further developing and using the tools today.
Following the North Sea Piper Alpha oil rig accident in 1988 and subsequent Cullen inquiry, new and safer maintenance procedures were introduced. One of the most significant changes was the restriction in the use of welding repairs (hot work) in the maintenance of plant and pipework due to the risk of fire and explosion. Research at Newcastle provided a novel engineering model that formed the basis for implementation of a new repair technology. This used fibre reinforced polymer wraps to restore the integrity of pipes without `hot work' or any interruption of production, thus minimising operational costs and increasing worker safety. This new technology has now become industry standard with new ISO and ASME standards for pipeline repair established as mandatory standards in 2006 and 2008 respectively (ISO/TS 24817 — Composite repairs for pipework; and ASME PCC-2, Repair of pressure vessels and piping). The period 2008-2013 has seen considerable expansion, worldwide, of an industry offering materials and support services to enable composite repairs to be designed and carried out.
In recognising the challenges facing a competitive, globalised pharmaceutical industry, the Advanced Bioprocessing Centre team at Brunel University have pioneered the technology and a methodology for speeding up the R&D, purification and manufacture of new drugs.
Already being adopted by market leading pharmaceutical companies, the High Performance Counter-current Chromatography presents a new technological platform to generate significant reductions in development costs; an increase in yield and a greener waste process.
The research supported by eight Research Councils grants totalling £3,557,168 led to establishing a spin-out company, Dynamic Extractions, which today operates a commercial enterprise with £1M turnover in partnership with Brunel.
Metamaterials deliver electromagnetic properties not available in natural materials. Transformation optics replaces the ray picture of Snell's law with the field lines of Maxwell's equations and is an exact description of classical optics. These powerful concepts, originally developed by Prof John Pendry, have engendered massive interest in the electromagnetic community encompassing radio frequency (RF) through to optical applications. His advice is sought by numerous companies and these concepts are now filtering through into products. In the last 5 years there has been great involvement of industry and particularly of the defence establishment in the USA who run several multi mullion dollar programs on metamaterials based at DARPA, WPAFB and Sandia. A company, KYMETA, was formed in 2012 to market this technology with $12M of investment funding, and is developing a laptop-sized antenna that gives instant Internet hotspot access anywhere in the world, with an ultimate application allowing cheap and fast Internet connections for the everyday consumer. In the UK, BAE Systems is using metamaterials for several applications including compact, directional antennas.
Components built using 3D composite manufacturing methods developed by Cranfield are now flying on the Boeing 787 Dreamliner aircraft. This is the first use of structural composites in commercial aircraft landing gear. The prototypes were assembled and reinforced using robot automated technology developed at Cranfield.
Cranfield's work has extended the use of composite materials into critical landing-gear systems, allowing Messier-Bugatti-Dowty to contribute to the use of 50% composite materials for the airframe of the new 787, delivering weight reduction and better fuel economy.