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1h. The Profitable Lifetime Index (£PLI) is a reliable basis for genetic improvement of dairy cattle productivity, health, welfare, longevity and environmental impact

Summary of the impact

Impact: Economic / animal health and welfare / environment: Improved profitability and sustainability of the UK dairy industry.

Significance: The use of the Profitable Lifetime Index (£PLI) increased the profitability of the dairy sector by an estimated £634M in 2008-2013 and reduced the greenhouse gas emissions from the sector by an estimated 8.4%.

Beneficiaries: Dairy producers, breeding companies, general public/environment, dairy cattle welfare and health.

Attribution: Drs Wall, Mrode (SRUC), and Brotherstone (UoE), Profs. Coffey, Simm, Stott, Veerkamp, Oldham (SRUC), and Woolliams (UoE/Roslin)

Reach: UK dairy industry. Tools developed, such as the routine recording of body condition score, and using these data in national genetic evaluations, have been widely adopted internationally, including in major dairy genetics exporting countries such as the USA, Canada, the Netherlands and New Zealand.

Submitting Institutions

University of Edinburgh,SRUC

Unit of Assessment

Agriculture, Veterinary and Food Science

Summary Impact Type

Economic

Research Subject Area(s)

Engineering: Food Sciences

09_Dairy farm profitability is enhanced by the application of quantitative genetics.

Summary of the impact

Impact on productivity, the economy and the environment: UK dairy farmers can select the best animals for breeding using analysis of a wide range of traits, leading to improved productivity, greater efficiency and reduced environmental impact, because of UoE research creating a UK Test Day Model (TDM) and an overall Profitable Lifetime Index (PLI)

Beneficiaries: The principal beneficiary is the dairy industry, specifically dairy farmers who are able to generate higher profits. This has benefits for UK consumers and the economy by keeping milk prices lower. The reduction in greenhouse gas emissions associated with more efficient dairy farming practices has global benefits.

Significance and Reach: The genetic evaluation system enabled by the PLI and TDM has resulted in a financial benefit to the UK dairy industry of an estimated £440M over the period 2008-2013.

Attribution: The quantitative genetic research was led by Dr Sue Brotherstone and Professor Bill Hill of the School of Biological Sciences, UoE, with colleagues at Roslin Institute (UoE; UoA6) and SRUC (also returned with UoE in UoA6) as described below.

Submitting Institution

University of Edinburgh

Unit of Assessment

Biological Sciences

Summary Impact Type

Environmental

Research Subject Area(s)

Biological Sciences: Genetics

The breeding of novel types of oat with improved grain composition has changed retail and consumers’ habits to the benefit of the UK oat crop as a healthy human food and as a high value livestock feed.

Summary of the impact

Oats are recognised as a healthy grain reducing the risk of coronary heart disease and as a valuable grain for livestock feed. Research within BEAA has provided the genetic, physiological and agronomic knowledge that underpins the breeding of high yielding husked and naked oat varieties that meets the needs of end-users in the human food and livestock sectors. BEAA bred oat varieties account for approximately 65% of the UK market and have a significant impact on health and welfare, the economy and on production and support the expanding instant oat breakfast market sector that alone is worth £160million per annum.

Submitting Institutions

Aberystwyth University,Bangor University

Unit of Assessment

Agriculture, Veterinary and Food Science

Summary Impact Type

Health

Research Subject Area(s)

Biological Sciences: Genetics, Plant Biology
Agricultural and Veterinary Sciences: Crop and Pasture Production

1e. Marker-Assisted Selection to breed for resistance to Infectious Pancreatic Necrosis in Salmon

Summary of the impact

Impact: Economic, animal health and welfare: Genetic markers have enabled selection of salmon lines with improved virus resistance

Significance: UK salmon industry benefit estimated at ~£26 million/annum GVA following identification of a genetic trait conferring resistance to an economically devastating viral disease.

Beneficiaries: Salmon farming industry, consumers

Attribution: Work performed by Houston, Bishop, Woolliams and Haley (Roslin Institute, now part of UoE).

Reach: Aquaculture industry internationally, i.e. Europe and South America (Chile).

Submitting Institutions

University of Edinburgh,SRUC

Unit of Assessment

Agriculture, Veterinary and Food Science

Summary Impact Type

Environmental

Research Subject Area(s)

Biological Sciences: Genetics

1d. Breeding a scrapie resistant international sheep flock

Summary of the impact

Impact: Economic, public policy and animal health and welfare: Selective breeding based upon identification of PRNP genotypes can eliminate animals that are susceptible to scrapie from the flock.

Significance: UK sheep meat exports are worth >£380million. Breeding for scrapie resistance protected the sheep industry from similar damage to that inflicted by BSE on cattle and the UK economy.

Beneficiaries: Farmers, animals, consumers

Attribution: Professor Hunter and Dr. Goldmann (Roslin Institute, now part of UoE) identified polymorphisms of the PrP (PRNP) gene linked to scrapie susceptibility and resistance in sheep.

Reach: International, programmes breeding for resistance to scrapie in sheep are now used in the UK, Europe and USA.

Submitting Institutions

University of Edinburgh,SRUC

Unit of Assessment

Agriculture, Veterinary and Food Science

Summary Impact Type

Technological

Research Subject Area(s)

Agricultural and Veterinary Sciences: Animal Production, Veterinary Sciences
Medical and Health Sciences: Medical Microbiology

A genetically informed management plan for breeding African Wild Dogs in captivity

Summary of the impact

African Wild Dogs (Lycaon pictus; referred to as `AWDs' hereafter for brevity) have been classed as endangered by the International Union for Conservation of Nature (IUCN) for 22 years. Large, well-managed captive breeding programmes provide a safety net to restore wild populations. However, the management of the AWD population has been difficult owing to an incomplete family record of captive AWDs, which risks introducing genetic disorders caused by inbreeding. A genetically informed management plan developed by University of Glasgow researchers has provided a genetic measure of diversity and establishes a genetically informed pedigree, which is used in the European Endangered Species Programme for African Wild Dogs. This has introduced a more informed means to manage the captive AWD population, to maintain the genetic diversity of the species across the European zoo network (roughly half the world's captive AWD population), with 53 zoos in 16 European countries (and Israel) currently participating.

Submitting Institution

University of Glasgow

Unit of Assessment

Biological Sciences

Summary Impact Type

Environmental

Research Subject Area(s)

Environmental Sciences: Environmental Science and Management
Biological Sciences: Genetics

Developing tools to restore fertility in dairy cows

Summary of the impact

Fertility of dairy cows has been in decline since the 1970's and this has threatened sustainability of the dairy industry worldwide. Research led by Nottingham University (UoN) identified key drivers of fertility and provided genetic and nutritional tools for the industry, to help combat the decline. The genetic tool was the UK Fertility Index, which is used universally by breeders for national and international bull selection. The nutritional tool, which is widely applied by international feed companies, used the concept that nutritional manipulation of insulin enhances fertility. Evidence shows that use of these tools between 2008 and 2013 has reversed the decline, and fertility is being restored. This has brought commercial benefits for breeding companies, cattle food producers and farmers and had a positive impact upon animal welfare.

Submitting Institution

University of Nottingham

Unit of Assessment

Agriculture, Veterinary and Food Science

Summary Impact Type

Technological

Research Subject Area(s)

Engineering: Food Sciences
Medical and Health Sciences: Paediatrics and Reproductive Medicine

The breeding of high sugar grasses (HSG) has had a positive effect on UK greenhouse gas mitigation and on livestock production

Summary of the impact

BEAA research on high sugar grasses (HSG's) led to the breeding of HSG varieties that have had a significant impact on the contribution of grassland to livestock feeding across the UK. Their impact on the economy, commerce and the production of livestock products has been significant in the UK and increasingly in other countries. HSG varieties currently account for over 28% of the perennial ryegrass seed sales in the UK, with over 150,000 ha sown in the UK alone of these varieties since 2008, as their positive benefit on the economics of livestock production from grass and environmental benefit through reduced N pollution from livestock production is recognised.

Submitting Institutions

Aberystwyth University,Bangor University

Unit of Assessment

Agriculture, Veterinary and Food Science

Summary Impact Type

Environmental

Research Subject Area(s)

Biological Sciences: Genetics, Plant Biology
Agricultural and Veterinary Sciences: Crop and Pasture Production

Novel genetic marker-assisted breeding produced a new pearl hybrid grown for 700,000 ha of drought-prone areas in northern India which has improved food security of three million people.

Summary of the impact

Research using novel techniques of genetic marker-aided selection enabled the development of new high yield, disease- and drought-resistant pearl millet hybrids, of which HHB67-Improved was released throughout India. HHB67-Improved is the first product of marker-assisted breeding to reach cereal producers in India and has spread rapidly since its release, preventing yield losses to downy mildew of up to 30% (valued at £7.8M) per year, and providing £2.6M additional annual grain yield. By 2011, it was grown on over 700,000 ha and currently three million people have improved food security as a direct result of this international development focused work.

Submitting Institutions

Aberystwyth University,Bangor University

Unit of Assessment

Agriculture, Veterinary and Food Science

Summary Impact Type

Technological

Research Subject Area(s)

Biological Sciences: Genetics, Plant Biology
Agricultural and Veterinary Sciences: Crop and Pasture Production

Foal Immunodeficiency Syndrome - Control of a Fatal Equine Genetic Disease

Summary of the impact

Foal Immunodeficiency Syndrome (FIS) is an emerging fatal inherited equine disease which has caused much concern in the equine industry. Research at the University of Liverpool (UoL) into the genetic basis of this disease has identified the genetic mutation and developed a carrier test which led to equine population screening to understand the spread of this disease (>40% adult carriers in one breed, Fell ponies) and provided a tool for vets and owners to design selective breeding programmes to eradicate the disease. Since the introduction of the test in 2010, the number of cases has drastically fallen (only 1 detected in any breed in 2012) and FIS spread into other breeds is now considered most unlikely.

Submitting Institution

University of Liverpool

Unit of Assessment

Agriculture, Veterinary and Food Science

Summary Impact Type

Technological

Research Subject Area(s)

Biological Sciences: Genetics

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