Log in
The University of Nottingham (UoN) has been at the forefront of research into intramammary infections during the non-lactating (dry) period in dairy herds. This research, disseminated through presentations to key stakeholders and veterinary textbooks, has changed clinical and farmer practices as evidenced by international disease/welfare reports, national control programmes and increased use of non-antibiotic teat sealants. The work has culminated in the launch of a novel software tool that uses the research findings to provide a farm-specific decision aid, which benefits the business activities of dairy farmers and improves animal health and welfare.
A novel, reliable, non-invasive and rapid method has been developed to detect excretion of Mycobacterium bovis, the causal agent of bovine tuberculosis (bTB), into the environment ("shedding") by wildlife hosts. This test has been used to establish the efficacy of the bTB vaccine on reducing environmental contamination by shedding of M. bovis in the faeces (from January 2010). It has also become an important monitoring tool used by VisaVet (European Veterinary Health Surveillance), targeting bTB in wild boar and red deer (from July 2010) to establish bTB reservoirs and take action to protect the cattle stocks. Farmers will benefit and now be able to monitor environmental contamination by M. bovis, which allows them to establish biosecurity best practice.
The method includes both a presence/absence score and a quantitative assay of infectious disease load in faecal matter in the environment. This is the first standard assay to determine environmental contamination, the main route for disease spread to cattle, and allows evaluation of the impacts of vaccination, culling and increased movement of badgers during disease- management strategies. This test also enables precise monitoring of cattle herds infected with bovine tuberculosis (bTB) as it advances from the South West to the North East of England.
Impact: Economics, policy, animal and human health: In 2006, SoS (a Public Private Partnership-PPP) was established involving: University of Edinburgh, a pharmaceutical company, a charity, and the Govt. of Uganda to control sleeping sickness by eliminating Trypanasome carriage in cattle. The prevalence of trypanosomiasis has been reduced by 75% and sleeping sickness cases have fallen year on year since the PPP was established and Uganda has received a cost benefit between US$125 and $400M
Beneficiaries: The Ugandan population, Ugandan Cattle population.
Significance: Sleeping sickness, which is difficult to diagnose and treat in humans, is often fatal. Ten million Ugandans are at risk from sleeping sickness. SoS established a veterinary network in Uganda producing
Attribution: Professor Welburn (University of Edinburgh, UoE) founded SoS and developed essential diagnostic techniques.
Reach: SoS provides a model for the elimination of the disease across sub Saharan Africa in an economically sustainable fashion - with over 22 million people at risk.
Dairy-cow herds in the UK and overseas, together with the dairy farming industry, are benefiting from strategic animal-husbandry changes and lameness-control programmes underpinned by research undertaken at the University of Bristol since 1997. The dissemination by the UK Dairy Levy Board of national Standardised Lameness Scores (the DairyCo Mobility Scoring system, launched in 2008) and of Husbandry Advisory Tools (the DairyCo Healthy Feet Programme, launched in 2011) was a direct result of Bristol's work. It has led to the widespread adoption of lameness scoring as a farm-management tool, the inclusion of lameness assessment within certification schemes and a nationwide network of trained `mobility mentors'. Where implemented, this advisory support has resulted in a significant drop in lameness prevalence, thereby improving welfare and reducing the economic losses associated with treating and culling lame cows. Successful engagement with industry groups throughout the research process has ensured that scientific outputs have been rapidly implemented within the farming community. This approach has been adopted internationally with the scoring system being used by Europe's largest dairy company and a modified version is also being promoted by the New Zealand dairy industry.
Impact: Economic / animal health and welfare: Established health schemes to control Bovine Viral Diarrhoea (BVD) on Scottish farms and subsequently underpinned the rationale for cost-effective control strategies that have been adopted in health schemes around the UK. The farm-level savings to the industry from future eradication are estimated by Scottish Government to be £50- £80m.
Significance: BVD is a major endemic disease of cattle in Scotland costing the dairy industry about £38M per year and an additional £11M to consumers.
Beneficiaries: Farmers, cattle, animal health authorities.
Attribution: Professors Gunn and Stott (SRUC).
Reach: The associated health schemes began in Scotland (HI Health) and now operate throughout Britain (UK CHeCS (Cattle Health Certification Standards) Health Scheme). The research underpins BVD control schemes in Ireland and other EU Member States resulting in an avoided output loss of between €500 to €4,000 per dairy farm per year.
The University of Nottingham (UoN) led research that resulted in the design, evaluation and national implementation of a new approach to mastitis control on British dairy farms; the `DairyCo Mastitis Control Plan'. The programme, which commenced in 2009, was implemented on farms holding 10-15% of all British dairy cows. The uptake of the scheme is continually increasing and has generated savings to the British dairy industry to the order of £5-10M per annum.
The parasite Neospora caninum is the leading cause of abortion in cattle in the UK, resulting in around 6,000 abortions per year; and a $1.3b pa international problem. There are no effective drugs or vaccines to control neosporosis. University of Liverpool (UoL) research on the development of diagnostic tests, understanding the pathogenesis, epidemiology and transmission of N. caninum has made an important contribution to developing best practise herd health schemes, now offered by the Animal Health and Veterinary Laboratories Agency (AHVLA) and by a commercial company `myhealthyherd', to eradicate N. caninum infection from a herd. This has enabled cattle farmers to improve their businesses by reducing abortion rates and other costs associated with neosporosis.
Despite increasing surveillance, outbreaks of bovine tuberculosis (bTB) in the UK have steadily increased over the past two decades, with the disease now costing an estimated £100 million per annum in test and slaughter costs, and compensation payments.
Research by Professor Wood and Drs McKinley and Conlan has determined that successful control efforts will depend upon within-herd surveillance and also on reducing reintroduction from external sources; these results have directly altered the Department of Environment, Food and Rural Affairs' (Defra) new (July 2013) bovine TB strategy for England, which directly cites Dr Conlan's research when justifying changes in proposed regulations. On publication this research prompted questions during bovine Tuberculosis debates in both Westminster and the Scottish Parliament by Andrew George (MP, St. Ives) and Helen Eadie (MSP, Cowdenbeath) respectively. The work has also received national and specialist media coverage raising public awareness and understanding of bTB control in cattle.
Research undertaken at Strathclyde during 2006-2009 produced a decision support platform combining artificial intelligence with low power wireless sensor technology, which was capable of alerting farm staff to animal conditions requiring human intervention. ETS Ltd, a privately owned University Spin-out company was founded in 2009 to develop and market the new technology, and now employs 7 full time staff. Since 2010 more than 250 farms in the UK and Europe have adopted the technology, enabling them to reduce operating costs, maximise milk revenue, with an estimated increase of £10k per 100 cows per annum. The new technology has also improved the performance of other existing businesses and has helped retain jobs in the supply chain in Scotland.
In the UK, one in seven dairy calves dies annually during rearing. Herd profitability is reduced further by calfhood disease and suboptimal growth rates, delaying age at first calving and reducing milk output. Professor Claire Wathes's longstanding scientific interests in dairy cattle reproduction and development have led to a broader farming industry appreciation of this issue, and to new approaches that address the economic loss and welfare issue it represents. Her results are now incorporated into professional and practical advice from DairyCo (industry levy board); Defra; farm veterinarians; commercial feed companies; opinion leaders in dairy farming; and the specialist farming media.