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The underpinning research has led to a methodology for cost-effective monitoring systems to interpret complex and emergent conditions in real-world applications. There are ten different organisations utilising the technology, benefitting the UK economy and health care provision, both nationally and internationally. These include MAST Group Ltd, Electricity North West Ltd, TMMHRC (India) and the Milestones Trust (Bristol). The impacts are (i) Economic: improving business capabilities and UK company profit margins (ii) Societal: benefiting health sector organisations in India and in the UK through improved diagnosis and care for the elderly and vulnerable; and (iii) Environmental: reducing waste and carbon footprint.
BEAA research has impacted positively on commerce in brewing and biotechnology companies worldwide through continuous collaboration with Aber Instruments, an AU spin-out company formed to commercialise university research. Aber Instruments has supplied over 1000 fermentation monitoring systems world-wide for the on-line measurement of viable biomass concentration, providing improvements in speed and accuracy over previous off-line, culture or stain-based procedures. On-line, real-time monitoring of viability during fermentation reduces costs and improves product quality, leading to practitioners in large breweries including Anheuser Busch, SABMiller, Inbev, Coors, Diageo, Heineken, Suntory and San Miguel adopting the Yeast Monitor as part of their standard operating procedures. The new Futura instrument, which utilises the same technology developed from BEAA research, was launched in 2009 and is now used by major biotechnology companies including Genetech, Novo, Biogen Idec, GlaxoSmithKline, Centocor, Sandoz, Eli Lilly and Genzyme to monitor biomass in a much wider range of fermentations.
Platinum Group Elements (PGE) are critical strategic metals because of their unrivalled applications in catalysts, fuel cells and electronics and cancer therapies. Research and analytical methods developed at Cardiff have impacted on exploration for new PGE deposits, and more efficient processing of PGE ores by international mining companies. A key milestone between 2009 and 2012 was the discovery of a 3 billion year old giant impact crater in West Greenland. This discovery is of major economic significance because all craters previously found in this size class are associated with multi-billion dollar mineral and/or hydrocarbon resources. It led to an intellectual property transaction worth CDN$ 2.1 million and discovery of nickel and PGE deposits in Greenland by North American Nickel Incorporated.
From strains within a single carbon fibre to deflections in a bridge, dam or railway line, accurate measurement is vital to industry and public infrastructure. In many engineering contexts, traditional approaches to measurement are inadequate or involve unacceptable costs and delays. These shortcomings have been addressed by the University of Bristol's research into high-precision, video-based metrology and its application through Imetrum, a spin-out company. Imetrum was founded in 2003 and launched its first product - the Video Gauge - in 2007. In the area of mechanical testing, the company has brought the first video-based extensometry system that can be supplied calibrated to international standards to market. For structural monitoring and safety inspections, deformation measurements are usually required. The Imetrum system is being used to precisely measure such deformations in rail bridges and other vital parts of the infrastructure without costly and inconvenient interruptions to their operation. Imetrum has approximately doubled its turnover each year since 2007. [text removed for publication].
Innovative research at Strathclyde University, embodied in its spinout Diagnostic Monitoring Systems (DMS) Ltd, has enabled the Glasgow-based company to become the premier supplier of ultra-high frequency (UHF) systems for detecting harmful partial discharge (PD) activity in high-value gas insulated substations and power transformers. Annual sales rose from £6.7M in 2008 to £11M in 2012, and its staff doubled to 56 employees. DMS' equipment is utilised in 27 countries, with total exports over 2008 - 2013 exceeding £45M. A sustained partnership with Strathclyde has yielded new sensor technologies and secured mainstream international recognition for UHF PD detection techniques, which are being incorporated within a new IEC standard. Economic value of Strathclyde's UHF technology was further emphasised in 2009 when DMS was acquired by Qualitrol, part of the US $46B Danaher Corp that owns numerous global engineering brands including Tektronix, Fluke, Leica Microsystems and Gilbarco Veeder-Root.
Cardiff University research led to second-generation chemiluminescent technology. The invention allowed for internal amplification control in nucleic-acid based clinical diagnostic assays for infectious disease and produced results with greater accuracy and fulfilled previously unmet regulatory standards. Adopted by the market leader in nucleic acid diagnostics (a sub-licensee of Cardiff University) the Cardiff technology is used globally in more than 60 million in vitro diagnostic tests annually. Sales of the tests approach $500 million per year and the sub-licensee was subsequently sold for $3.8 billion.
Economic impact is claimed through the growth of the biopharmaceutical spin-out company Q Chip Ltd. During the REF period, this has created 19 new jobs, £7.5M investment, a new Dutch subsidiary (Q Chip BV), and staged-payment, six figure contract sales to four major international pharmaceutical companies.
Q Chip has generated over £928K in contract sales from the pharmaceutical industry from 2008-2012, with further sales of over £1M projected in 2013-14.
Originally established by Professor David Barrow in 2003 from his micro technology research, Q Chip has developed new processes and miniaturised equipment to encapsulate materials, including drugs, within uniform polymeric microspheres as injectable therapeutics.
Economic gains by oil and gas companies, improvements in professional practice in hydrocarbon exploration, and environmental benefits from identifying CO2 disposal sites have been achieved through a Cardiff-led consortium with industry. Building on research carried out since 2004, ten of the largest oil companies in the World have contributed to and benefited from understanding how faulted caprocks behave under specific geological conditions. Research at Cardiff has shown which families of faults and fractures make caprocks highly permeable, thus improving Industry's ability to predict if caprocks are able to prevent oil and gas reaching the surface.
3D scanning technology has enabled multiple opportunities for innovation in diverse areas such as manufacturing, design, and the arts. However, full utilisation of this technology requires not just the scanning hardware, but accompanying software that can build meaningful, editable models. This development has been pioneered by research conducted in the School of Computer Science and Informatics, at Cardiff University. Innovative algorithms for reverse engineering and digital shape reconstruction were devised that enabled the reconstruction of complex computer aided design (CAD) models from data captured by 3D scanners. The algorithms have been endorsed by Geomagic Inc, a market leading American software corporation (recently acquired by 3D Systems), that has subsidiaries in Europe and Asia and global distributors, and incorporated into their software product suite. This is accessed by nearly 10,000 licensed users worldwide, who have applied the product for industrial applications including aerospace and automotive engineering, product design, cultural heritage preservation, and healthcare. Accordingly, the impacts claimed are twofold: a) economic gain manifesting in the benefits to Geomagic and a plethora of end users who have utilised the software, b) impact on practitioners and professional services in diverse domains.
Slope ALARMS is a novel low-cost sensor that detects acoustic emission and warns of the early signs of impending landslides. It has been developed and patented by Dixon at Loughborough University. British, Italian, Canadian and Austrian organizations with responsibility for vulnerable infrastructure have employed Slope ALARMS sensors since 2008 in locations with high landslide risk. Measurements have provided information on displacement rates and this is making a significant contribution to assessment of slope hazards. The invention has won awards and generated interest globally, raising public and professional awareness of landslide problems and the use of Slope ALARMS.