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In the UK, 20-25% of the population (around 15 million people) sufferer from allergic rhinitis (hay fever) resulting in about 4 million `sick days' per year. Research undertaken by the National Pollen and Aerobiology Research Unit (NPARU) over a period of 20 years has resulted in the development of a national pollen forecasting system for the UK which has had direct benefits on the health and wellbeing of hay fever sufferers. This research has also raised awareness of the importance of pollen information for sufferers, fed into policy on allergy services (and subsequently practice of these services), underpinned training of health professionals, and informed clinical trials of anti-allergy products and devices.
Techniques that can produce detailed chemical information rapidly and non-destructively for many forensic applications have been developed by Queen's University Belfast based on Raman analysis. The techniques have been adopted by the Forensic Science laboratory in Northern Ireland (FSNI) to trace the source of seized drugs, identify novel psychoactive substances ("legal highs") and study paint evidence. More than 2000 cases of supply/possession of ecstasy drugs, 947 paint casework samples and 100 'legal highs' have been analysed. Other law enforcement agencies are now adopting the methods developed at Queen's.
Research conducted by our International Boundaries Research Unit (IBRU) since the 1990s has improved the understanding of boundaries and boundary-making and developed end-user resources in the form of databases and digital maps. IBRU has developed processes and techniques which support peaceful dispute avoidance and resolution through an expanded notion of boundary-making on land, along rivers, and at sea. Our work has had direct impact on a range of geopolitical conflicts and disputes, particularly on boundary demarcation and dispute resolution within Africa. It has also shaped practitioner debate over jurisdictional issues in the Arctic and improved the representation of river boundaries in globally-used geospatial data products.
Clench's research on Matrix Assisted Laser Desorption Ionisation - Mass Spectrometry Imaging (MALDI-MSI) technologies has impacted directly on pharmaceutical industry practice regarding studies of drug distribution studies in biological tissues, providing increased information, more rapidly. Companies have benefitted from long-term relationships with Clench's Bioanalysis Research Group and seek its expertise for consultancy purposes. Former members of Clench's group hold key positions in industry, implementing and further developing these technologies. Francese has had significant success in applying MALDI-MSI to analysis of latent fingermarks for forensic applications benefiting Home Office scientists and crime scene investigation units. Research advances in MALDI-MSI by Clench and Francese are patented and exploited via licensing.
In a series of papers published from 1999 on, Aitken (Maxwell Institute) and collaborators applied Bayesian statistics to develop a methodology for the quantification of judicial evidence derived from forensic analyses. They proposed and implemented procedures for (i) determining the optimal size of samples that should be taken from potentially incriminating material (such as drugs seized); and (ii) the estimation of likelihood ratios characterising evidence provided by multivariate hierarchical data (such as the chemical composition of crime-scene samples). Their procedures have been recommended in international guideline documents (including a 2009 publication by the United Nations Office on Drugs and Crime) and have been routinely used by forensic science laboratories worldwide since 2008. The research has therefore had an impact on the administration of justice, leading to a better use of evidence and accompanying judicial and economic benefits. Examples are given from laboratories in Australia, Sweden and The Netherlands.
Brassica production contributed £245.7m to the UK economy in 2012 and is growing year on year.i Research described below has led to the development of simple to use hand-held devices which enable brassica growers to identify the presence of a specific plant disease in the air or soil. With this knowledge, the grower can make an informed decision about when to plant a new crop or to spray an existing crop. This benefits the grower economically through a decrease in losses to disease and lower pesticide costs. Beyond the benefits for the grower, the reduction in pesticide use is consistent with UK and European policy on the environment.
Queen's University Belfast has developed a number of biocatalytic processes for the production of pharmaceutical intermediates which have been applied commercially. The most significant involved Vernakalant, a new drug for treatment of the most common form of irregular heartbeat, now available in the EU, and currently awaiting approval in the USA and Canada. In addition, QUB has sold £300,000 worth of bioproducts and through the collaborations with Almac Sciences facilitated the initiation of their biocatalysis business which currently is a multi-million revenue earner for Almac Sciences and employs 30 staff, including 15 PhD graduates from the Queen's group.
Since the 1980s, there has been a wave of global activity seeking improved control of money laundering and confiscation of crime proceeds. This set of research studies, based around the work of Professor Mike Levi, constitutes core empirical analysis of the scale of financial crimes, and what can be properly said about the impacts of social and formal control measures against them. The studies have informed and helped to shape the fraud, money laundering and organised crime strategies of the UK Home Office, UK enforcement agencies, and international bodies such as the EC Justice and Home Affairs and IMF post-2008.
A team at Bristol University has played a central role in the development of new methods for assessing water quality in rivers and lakes. These are making it possible for the water industry to more reliably assess water quality and identify sites where remedial measures must be applied to meet the new standard of `good ecological status' as required by the European Union Water Framework Directive (WFD), which passed into UK law in 2003. The innovative, diatom-based tools were used in 2008 and 2009 to assess all targeted surface waters (rivers and lakes) in the UK and Ireland, leading to massive investment in infrastructure. This has opened up the prospect of higher quality water in lakes and rivers - something that the public and environmental organisations demand. Over the next few decades, the investment will bring an estimated benefit of £200 million to residents in England and Wales alone.
The case study examines the far-reaching impact of David Mead's research over the past ten years, all undertaken while at UEA, into the law that regulates and guarantees peaceful protest and into the policing of demonstrations. His research has informed public policy in the UK and in Europe (Joint Committee on Human Rights (JCHR) and the Organisation for Security and Cooperation in Europe (OSCE)), been relied on by practitioners before the courts up to and including the Supreme Court (in both the UK and New Zealand), been cited by the European Court of Human Rights, led to providing expert evidence before the High Court and assisted NGOs (such as Greenpeace).