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Healthcare Associated Infections (HAI) can be an unintended consequence of healthcare delivery. They are caused by a range of organisms but are often preventable. GCU-led research has reduced avoidable infections in healthcare in the UK and Europe by stimulating policy debate and investment in new healthcare practice and influencing policy decisions, evidence guidelines, and educational practices. Important changes have been made to national and international approaches to meticillin-resistant Staphylococcus aureus (MRSA) screening with cost savings of £7.5 million to the NHS. 28 European countries now use the HAI point prevalence survey validation method determined by our research.
As a direct result of methodological research led by Professor Ray Pawson at Leeds, `realist evaluation' has provided a new lens through which to assess and develop social programmes. It has critically changed the apparatus of evidenced-based policy and the way in which policy research is commissioned and utilised. Through advisory work, training package provision, partnership-research and professional exchange, this `realist' perspective has formed a new standard in social programme evaluation, and is used by commissioners in the UK and internationally to frame their interventions across policy domains, including education, environment, criminal justice, and health and social care.
Life-threatening bacterial endocarditis occurs on previously damaged cardiac valves. Established dental practice has been to administer antibiotics to patients who are at risk. This practice has been linked with increased antibiotic resistance, which represents one of the greatest threats to public health.
Researchers at the University of Manchester (UoM) evaluated the evidence for this practice by undertaking a high quality systematic review (initially published 2004). The review has informed multiple international guidelines. Publication of the NICE guideline led to a fall in the unnecessary prescription of antibiotics from 10,727 to 2,292 per month, an approximate annual saving of £174,580.
Prof Tanner's research on surgical site infections (SSIs) has had a direct impact on both patient care and policy at local, national and international levels. It has resulted in a reduction in the number of SSIs, thus improving patients' quality of life, shortening lengths of stay in hospital and making substantial cost savings for the NHS. The research has led directly to the development of policy and guidelines for various bodies including the World Health Organisation, the Department of Health, NICE and the Joint Commission Accreditation Healthcare Organisations (USA), as well as locally in a number of NHS trusts. The post discharge SSI surveillance programme pioneered by Prof Tanner has led to an increase in the number of trusts in the UK undertaking post discharge surveillance.
This case study describes the impact of a programme of work led by Professor Fiona Dykes, within the Maternal and Infant Nutrition and Nurture Unit (MAINN), at UCLAN. The unit was established in 2000 by Dykes. The research conducted in MAINN is underpinned by a range of interpretive and critical theoretical perspectives; it also actively engages in knowledge translation in a range of local, national and global contexts. Impact is particularly highlighted with regard to Global Policy, namely the WHO Global Strategy for Infant and Young Child Feeding, National Policy to include the UNICEF UK Baby Friendly Initiative (BFI), Key DoH publications and the NICE agenda. http://www.uclan.ac.uk/research/environment/groups/maternal_and_infant_nutrition_and_nurture_ unit.php
Around 800 children are born each year in England with congenital permanent bilateral hearing loss and significant consequences for language development and social-emotional wellbeing. A 15-year programme of inter-disciplinary research made the case for the implementation of universal newborn hearing screening in England; now the NHS standard of care. Our subsequent studies developed a model of professional practice adopted internationally. Our tools to evaluate service quality have been adapted for use in the US, Canada and Australia. We have trained over 500 professionals in 6 countries.
This impact case study shows how work by members of the Violence Research Centre (VRC, director Professor Manuel Eisner) at the Institute of Criminology has contributed to policy change related to violence prevention in European countries, and the implementation of new violence prevention strategies at the levels of local and national governments. This impact is based on a stream of research by members of the VRC on the causes and the prevention of all manifestations of interpersonal violence, which is dedicated to generating practically useful knowledge.
Research in the area of childhood obesity has focussed on the development, implementation and evaluation of interventions. The APPLES Study (1996-99), the first UK school-based RCT was key in contributing to the evidence-base through wide dissemination including 3 BMJ (2001) publications, cited in NICE (2006) and WHO guidance (2004). Collaborations with academics, practitioners and the RCPCH led to the development of further community-based obesity treatment and prevention interventions including WATCH IT; early programmes e.g. EMPOWER, HELP and HAPPY and more recently innovative school-based initiatives involving school gardening. There is evidence of results being disseminated and influencing research, practice and policy.
This case study highlights a body of research around health Research Priority Setting (RPS) that assists policy makers in effectively targeting research that has the greatest potential health benefit. Empirical research on RPS led to organizational changes, and new policies within the Cochrane Collaboration along with new training resources and new RPS exercises. A research gap on inequalities in the risk of oral cancer in the English South Asian population led to an evidence synthesis exercise being carried out by the National Institute for Health and Care Excellence (NICE) and the formulation of a new public health guideline.
A team led by a Manchester Metropolitan University researcher developed the PROBE (Project Review, Objective Evaluation) methodology for evaluating healthcare information technology systems. This became a core part of the National Health Service (NHS) information strategy; in 1996, PROBE was accepted by the NHS Executive and HM Treasury as a central method for project review. PROBE has therefore brought significant benefits to clinical users, patients and NHS decision makers. Impacts described here relate to the use of PROBE to evaluate an electronic blood transfusion system. Specifically, through enabling the effective evaluation of the system, decisions by a health authority have been informed by research, clinical practices have improved, and levels of patient safety and confidentiality have risen.