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Non-Destructive Testing (NDT) is essential for the safe and efficient operation of high-value engineering plant in many engineering sectors. Research into ultrasonic arrays at the University of Bristol has had a major impact on NDT. Exploitation of the techniques developed has directly led to combined sales of around [text removed for publication]. For major end-users of NDT such as Ontario Power Generation, BAE Systems and Rolls-Royce, the research is leading to reductions in inspection costs, [text removed for publication]. In addition, highly-skilled engineers have been trained through an Engineering Doctorate programme and are now leading the industrial development of new array inspections based on underlying research performed at Bristol.
Brunel and The Welding Institute (TWI) have been pursuing collaborative research on the use of ultrasonic guided waves for the non-destructive testing of oil & gas pipelines, plates, rails, aircraft wires and other engineering materials since 2003. This successful collaboration has led to the creation in 2009 of the Brunel Innovation Centre (BIC), a joint venture between the two institutions based at TWI headquarters in Great Abington, Cambridgeshire, whose mission is to develop a financially sustainable research facility, drawing on Brunel's existing strengths, to complement and underpin the applied research and development activities at TWI. BIC's very successful operation has led TWI to make a significant re-alignment of their strategy and business model, from being a technology provider offering mostly short-term industrial research and consultancy to their members, to providing medium- and long-term research and postgraduate training at the new National Structural Integrity Research Centre (NSIRC), a joint facility being built at TWI headquarters. TWI received a grant of £22 million from the Regional Growth Fund to fund the new building, complemented by a £10 million investment from their own resources and a £15m HEFCE grant for equipment. NSIRC will become a world-class centre of excellence with a unique, industry-driven, integrated approach to research and postgraduate training in the field of structural integrity.
In Europe, there are over a million kilometres of oil pipelines, nearly a million kilometres of railway tracks, 600 offshore platforms and 300 suspension cable bridges. However, these assets are aging as they have been in use for many years and operate under harsh conditions. Brunel research team has advanced ultrasonic non-destructive testing (NDT) which has the ability to inspect buried pipes in their original place without removing the pipes or damaging their surrounding environment. In addition, the research was pursued to improve the NDT of rail tracks, storage tanks, flexible risers in offshore platforms and aircraft wires. The research has been commercially exploited and incorporated into Teletest Focus System Mark III by Plant Integrity Limited. The significant improvement has led Plant Integrity to terminate the sale of Teletest Mark III and introduce a new version, Teletest Focus System Mark IV, to the market in late 2010. Since then, Plant Integrity has doubled its turnover from sales of Teletest Focus System Mark IV from £1 million to £2 million in less than a year.
danceroom Spectroscopy (dS) is a cutting-edge, interactive public engagement project that allows people to literally step into an interactive molecular dynamics simulation. It has its origins in fundamental research carried out to understand ultrafast chemical dynamics in liquids. On a large scale, dS impact has arisen from its deployment in premier cultural settings in the UK and internationally, eg the London 2012 Olympics, London's Barbican Arts Centre, Ars Electronica (Austria), ZKM (Germany), and the World Science Festival (New York City). Statistics indicate well over 60,000 people have so far experienced dS, with audiences spanning ages from 3 to 73, and attracting those with a variety of interests including science, technology, art and education. Within the cultural and media sectors, dS has received several awards and substantial press attention, all of which has proven beneficial to several non-academic collaborators and partner institutions. The substantial momentum and opportunities available from dS are also being commercially exploited through a spin-out company called Interactive Scientific Ltd.
Imaging speed is of critical importance in most Magnetic Resonance (MR) imaging applications. King's College London (KCL) researchers have developed spatiotemporal undersamplings, or "k-t" methods, for three-dimensional (3D) imaging and corresponding image reconstruction methods that have increased the speed of imaging significantly, so that particular scans are now 5-7 fold faster. This has directly impacted the experience of the patient whose overall examination time has been reduced from more than 1 hour to less than 30 minutes depending on the application. The technology has been patented and has been implemented by Philips Healthcare, one of the three major manufacturers of MR equipment. A clinical solution platform for 3D MR cardiac perfusion and quantitative flow imaging, based on the technology developed at KCL, has also been launched by the Swiss company, GyroTools LLC.
Development of the World's first radiation-tolerant, wafer-scale (13 cm square) CMOS imager (Active Pixel Sensor) which presents exciting new potential for medical, scientific and technological imaging with much improved performance and lower life-time costs. This development fully met a Grand Challenge set by EPSRC and the imager, called Dynamite, is being exploited in on-going trials for prostate cancer radiotherapy at the Royal Marsden Hospital/ICR and for diffraction-enhanced mammography at UCL/Ninewells Hospital, Dundee, and proton therapy imaging with Wellcome Trust support. Dynamite won the IET Innovation Award for Electronics (2012). A spinout company, ISDI Ltd, was formed in 2010 to further custom CMOS imager design and provision. [text removed for publication]
This case study demonstrates both major societal (healthcare) and economic impact through making commercially available new and revolutionary medical diagnostic and therapeutic imaging technology, being delivered directly a new start-up company. It also exemplifiers the entire entrepreneurial pipeline from RC-UK Basic Technology funding to successful company creation.
Imperial researchers in Prof Paul French's photonics group demonstrated one of the first practical FLIM instruments in 1997 using a prototype gated optical intensifier (GOI) developed by Kentech Instruments Ltd and a home-built solid-state ultrafast laser. They subsequently pioneered the use of ultrafast supercontinuum sources (USS) for FLIM. Today wide-field time-gated FLIM is a commercial success and is being widely applied for biomedicine, including for imaging of diseased tissue [e.g. 5] and for FRET (Fluorescence resonance energy transfer) microscopy to assay protein interactions [e.g. 3, 4]. This research thus helped translate FLIM to a wider community, highlighting the potential for tissue imaging, cell biology and drug discovery. It stimulated about £5M of GOI sales for Kentech [section 5, source A], with whom they developed time-gated FLIM technology and applications, and millions of pounds worth of sales of supercontinuum sources for Fianium Ltd [B].
The techniques developed by the Warwick Ultrasonics Group focus on non-destructive testing (NDT) and address particular industrial needs as specified by industrial funders. These partners have included over 40 companies in the REF Impact period, ranging from SMEs to large multi- nationals operating in a range of sectors such as the heavy manufacturing, nuclear energy, food, petrochemical, transport, aerospace, power generation, equipment manufacturing and service industries. In particular, our spin-out company, Sonemat, has commercialised high-performance electromagnetic acoustic transducers (EMATs) developed by the research group, which has led to economic benefits for NDT equipment suppliers and their end users. Further industrial impact has arisen from novel NDT methodologies established by the Group.
Research at the University of Cambridge Department of Engineering (DoEng) has enabled accurate positioning to be added to 2D freehand ultrasound probes to enable the acquisition of large coherent blocks of high-resolution 3D ultrasound image data. The software code base developed in the DoEng was licensed to two separate companies, Schallware and MedaPhor, to enable them each to develop an ultrasound training product. Both companies have sold to more than 30 customers worldwide during the REF impact period; the Cambridge software had a key role in contributing to the innovation and quality of the products developed by both companies, and significantly increased the speed at which they were able to bring these products to market.