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A research programme of multi-centre clinical trials led by Professor Suzanne Hagen has established Pelvic Floor Muscle Training (PFMT) as an effective treatment for women with prolapse. Hagen's team has also successfully developed a Prolapse Symptom Scale and further tested a Prolapse Staging System to improve outcome measurement for women's health physiotherapists in the UK (20% and 15% clinical uptake respectively). The research has informed local, national and international guidelines and changed practice in 48% of UK physiotherapists. The research has also raised awareness of PFMT treatment for prolapse, with 70% of UK physiotherapists reporting an increase in prolapse referrals.
Reducing vehicle noise and vibration is a key quality objective in the automotive industry. Historically, the approach has been costly palliation late in the manufacturing process; now a new approach applied earlier in the vehicle development cycle has been devised by Loughborough University and Ford and implemented at Ford that has led to savings of $7 per vehicle with respect to clutch in-cycle vibration (whoop). Ford has reported savings of $10M over 5 years, whilst reductions in transmission rattle have led to 5% fuel efficiency gains [5.1]. Ford has made an investment of £240M in its engine and transmission work at Bridgend, which includes aspects of work reported here and has created 600 new jobs [5.2].
The impact of the research at Loughborough University from 1999 to date has transformed informational processes in Leicestershire Police and has been adopted by other Police forces across the UK and internationally. Within Leicestershire it has led directly to [5.1]:
Research at LU carried out from 2003 to 2011 has made a significant impact on the practical realisation of Open Access (OA) to scholarly publications at an international level. Research into publisher's Copyright Transfer Agreements underpinned the development of the SHERPA/RoMEO service, widely used by repository managers across Europe [impact 4.1]; a cost-benefit model of scholarly publishing in relation to the main routes to OA influenced the publishing industry, and research strategy amongst UK funding agencies [impact 4.2]; further research influenced Research Councils UK (RCUK) policy in relation to mandates [impact 4.3], and the work of the European Commission in the development of its digital agenda [impact 4.4].
The Physical Activity in Ageing, Rehabilitation and Health Research Group at Aberystwyth University has designed, implemented and evaluated rural Community Exercise Schemes (CESs), including GP referral of sub-clinical populations, and more specialised schemes, such as cardiac rehabilitation and falls prevention. This research has made a distinct and material contribution to the provision of CESs in the region by providing evidence to inform service planning and delivery, increase access to and engagement with services, improve health and influence professional standards, guidelines and training.
Both the introduction of legislation in England and Wales and the mandatory recording of interviews with criminal suspects has led to an increased examination and understanding of what happens in such interviews. Such studies have led to a prescribed framework, which following its implementation, has led to further study concerning its efficacy in gathering a reliable account. This case study, demonstrates how (through dissemination of the research and through working with practitioners) particular research findings concerning approaches to the investigative interviewing of suspects have influenced the practices of those users of the research both in this country and overseas.
The research impacted on public policy, practitioners and professional services both nationally and regionally. Specifically, it influenced the setting up and design of the Greater Manchester Challenge (GMC) in 2008, with unfolding educational and professional impacts: (a) measurable improvements in the performance of Greater Manchester schools; (b) participants have continued to collaborate and build on GMC interventions and findings; and (c) the GMC led to a set of recommendations about school-to-school collaboration.
Research at the University of Manchester (UoM) has changed the landscape of medical care and research in fungal infections internationally. The impacts include: the world's first commercialised molecular diagnostic products for aspergillosis and Pneumocystis pneumonia (£10m investment); pivotal contributions to the preclinical development (£35m investment), clinical developments and registrations of 3 new antifungals with combined market share of ~$2 billion; one (voriconazole, 2012 sales >$750m worldwide) now first line therapy for invasive aspergillosis with improved survival of 15-20%; and internationally validated methods to detect azole resistance in Aspergillus (an emerging problem partly related to environmental spraying of azole fungicides for crop protection).
The research impacted on both public policy and professional practice. Specifically the research has enabled the development of an overarching framework for linking interventions in social structures, families and schools, particularly at area level. This in turn has impacted principally (a) on organisational strategy and professional practice at local level; but also (b) on national policymaker decisions and processes involved in the transformation of the `Extended Schools' agenda; and (c) on thinking and strategy by policymakers in Europe and other countries internationally. Crucial to the impact process have been partnership relationships using a development and research (D&R) methodology with a wide range of local initiatives, together with support for change in national and trans-national policy in this field.
Bangor University's publications on medieval Arthurian literature c. 1350-1550, in particular on French and English medieval romances, have impacted on the local, national and international cultural life and heritage, economic prosperity of local tourist attractions, the enhancement of the theatrical audience experience (the Royal Shakespeare Company) and creative practice (King Arthur's Labyrinth). Dr Radulescu's work was vital to international TV and radio programmes on the Arthurian legend, and in 2011-13 to the development and enhancement of reading materials for the educated general public and developments in creative writing.