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From space science to medicine; the application of novel sensor technologies in healthcare

Summary of the impact

Space science and medicine share a fundamental requirement for radiation sensors of the highest possible sensitivity. The development of imaging detectors for major X-ray observatories such as the European XMM-Newton and NASA's Chandra provided the impetus for a broad-based, intensive programme of deliberate technology transfer from the Unit's Space Research Centre (SRC) into the life sciences and medicine. The resulting impact now extends far beyond the exploratory provision of prototype sensor technologies for biomedical researchers into the full-scale commercial exploitation of those technologies with industry partners in the UK and Europe and, in three separate cases, to early-stage patient trials. Impact is being delivered in clinical specialisms from oncology to ophthalmology; from neurotoxicology to emergency medicine. The impact delivery mechanisms — the hospital-based Diagnostics Development Unit (DDU) and the campus-based Bioimaging Unit — are themselves novel and have achieved national prominence as examples of best practice in the drive for economic return even from established blue skies research.

Submitting Institution

University of Leicester

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Other Physical Sciences

Next-Generation Airport Baggage Scanners Revolutionising Passenger Security Checks

Summary of the impact

Radiation physicists at the University of Surrey developed a unique X-ray imaging technology for high-speed real-time tomography (RTT) during 1997 to 2005. The originating research developed new X-ray methods for tomographic imaging of multiphase flow in pipes. RTT was then applied to security X-ray imaging, specifically the high-speed screening of aircraft passenger baggage. As a direct result of the research, a spin-out company from the University, CXR Ltd, was formed, and it was later acquired by Rapiscan Systems.

Surrey's imaging technology is now approved for use for automated explosives detection in the European aviation sector. In 2009, a prototype high-speed baggage system was trialled at Manchester Airport, which resulted in certification in 2012. The research has made a significant economic impact by leading to technology that created jobs in a purpose-built factory.

Submitting Institution

University of Surrey

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Other Physical Sciences
Information and Computing Sciences: Artificial Intelligence and Image Processing
Technology: Communications Technologies

Research affecting UK Government Space Policy and the UK Space Industry.

Summary of the impact

Space has been identified as an area of economic growth by the UK Government as a direct result of the 2010 Innovation and Growth Strategy (IGS) for Space. This study has resulted in a transformational change with the formation of the UK Space Agency, significantly increased investment and new opportunities. The Unit contributed critically to the IGS and resulting actions by stressing the underpinning nature of academic space research and providing academic lead on key recommendations of the IGS and its subsequent technology plan. The research has also significantly impacted a number of companies increasing their research and development and economic bases e.g. a Leicester based SME Magna Parva Ltd.

Submitting Institution

University of Leicester

Unit of Assessment

Physics

Summary Impact Type

Societal

Research Subject Area(s)

Physical Sciences: Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences

Medipix - High Energy Physics collaborators deliver technological breakthrough behind world’s most advanced X-ray detector

Summary of the impact

Medipix-based detectors are the best pixelated X-ray detectors available on the market and are commercialised by PANalytical under the brand name PIXcel. At the core of PIXcel is the Medipix2 chip, which was developed around a photon counting breakthrough conceived by the Medipix collaboration and is unique in its adaptability, high spatial resolution, high dynamic range and low noise. This product is the direct result of an exclusive license and a collaboration agreement between PANalytical and the Medipix collaboration, coordinated by CERN and comprising a further sixteen leading physics research institutes in Europe. The University of Glasgow is the only UK institution to be one of the four founding members of the Medipix1 collaboration.

Submitting Institution

University of Glasgow

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Other Physical Sciences
Information and Computing Sciences: Artificial Intelligence and Image Processing

The Centre for Electronic Imaging, industrially sponsored research benefiting the UK economy

Summary of the impact

Professor Holland's group, the Centre for Electronic Imaging (CEI), has a long-established collaboration with UK-based imaging specialist e2v that has enabled the company to grow its business in international space missions and increase competitiveness. The CEI has helped develop e2v's understanding of the processes at work in imaging sensors, and improved image sensor designs and test methodologies. CEI has also studied space radiation damage on the sensors, trained more than 30 engineers in testing of e2v products, and was instrumental in the company's successful £3.8m Regional Growth Fund award in 2012 — funding that will create around 100 jobs by 2016.

Submitting Institution

Open University

Unit of Assessment

Earth Systems and Environmental Sciences

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences
Technology: Communications Technologies

Supporting e2v Ltd. in developing capability as a supplier for major space science missions

Summary of the impact

Research conducted within the Department of Space and Climate Physics at UCL has had a significant impact upon e2v Ltd., a manufacturer of charge-coupled devices (CCDs). Through working collaboratively with e2v, UCL has helped the company to secure major contracts and business [text removed for publication]. This includes two contracts for the supply of CCDs for the European Space Agency (ESA) missions Gaia (€20 million) and Euclid (€10 million). Furthermore, the symbiotic relationship has contributed to the establishment of e2v as Europe's leading supplier of high-quality CCDs for space science applications and has underpinned an improved understanding of device design and optimisation within the company.

Submitting Institution

University College London

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Atomic, Molecular, Nuclear, Particle and Plasma Physics
Technology: Communications Technologies

Enabling space companies to deliver contracts and supporting growth of the space sector

Summary of the impact

UCL's research and development programme in space science and engineering enabled it to complete four major contracts with European and Canadian space companies between 2009 and 2011. These contracts were for the supply of equipment that will fly on European and Indian space missions, and for support of the ground testing of those space missions. The fact that these contracts were won by UCL in a competitive environment against low-cost industrial providers demonstrates that customers value the capability that UCL possesses. By acting as a specialist provider within the UK space sector supply chain, UCL enabled the prime contractors European Astrium Aerospace and Canadian Routes AstroEngineering Ltd. to deliver substantial commercial contracts with space agencies. Its provision of specialist input into these major contracts enabled UCL to also directly support the growth of the commercial space sector.

Submitting Institution

University College London

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences
Technology: Communications Technologies

The National Space Centre (NSC)

Summary of the impact

The National Space Centre (NSC), sited in the Abbey Meadows area of the City of Leicester, combines elements of museum and visitor attraction with an educational mission to attract 8-14 year olds to the Science, Technology, Engineering and Mathematics (STEM) subjects using the inspiration of space science and exploration. Since its opening on June 30th 2001, the NSC has welcomed almost 2.5 million visitors to its galleries and full-dome planetarium. Space science research within the UoA was a driving force in the establishment of the NSC and continues to contribute to its success. Members of the Unit serve as non-executive Directors on the NSC Operating Company (OPCO) Board and as Trustees, while others contribute to its Space Now public outreach programme and to the Space Academy teacher engagement project which began in the East Midlands region, but now has national scope. The claimed impact is not only related to outreach and quantitative educational outcomes, but also to long-term economic benefit to the City of Leicester, through the regeneration of a brownfield site in a disadvantaged inner-city district, now featuring the development of a science park with the National Space Centre as its focus.

Submitting Institution

University of Leicester

Unit of Assessment

Physics

Summary Impact Type

Societal

Research Subject Area(s)

Physical Sciences: Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences
Engineering: Aerospace Engineering

Inspiring public engagement in astronomy

Summary of the impact

The university's Bayfordbury Observatory is a working observatory that engages with the public via six Open Evenings and approximately 50 group visits a year, offering access to a wide range of facilities. Many of the 4,000 visitors annually report that they develop a first or renewed `enthusiasm for astronomy', or become `inspired to learn more' about what they have seen or heard from our researchers; some young people enthuse about `now wanting to be a scientist'. Science teachers taking an RCUK `cutting-edge' CPD astrophysics course also say that they have gained an `increased understanding of the subject', and `increased confidence in its delivery to pupils'.

Submitting Institution

University of Hertfordshire

Unit of Assessment

Physics

Summary Impact Type

Societal

Research Subject Area(s)

Physical Sciences: Astronomical and Space Sciences

2. THz detection from the distant universe to the international market

Summary of the impact

Research and Development activity at Cardiff University's Astronomy Instrumentation Group (AIG) has been commercialised and made available to the international market. Sales have been made to fields including bio-molecular spectroscopy for health science, plasma fusion diagnostics for sustainable energy, and remote atmospheric sensing. This has resulted in economic impact through:

  • revenue generated by the Group's spin-out company, QMCI Ltd., which has demonstrated increased global sales of unique AIG technology through commercialisation of the latest THz detection systems and advancing product development and performance;
  • exploitation by third parties in the alternative energy and security markets.

Submitting Institution

Cardiff University

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences
Technology: Communications Technologies

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