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Research on the relationship between women's working lives, occupational exposures and breast cancer, which uses detailed work histories as a means of identifying toxic exposures, has found there to be an elevated risk for women working in agriculture, bars and gambling environments, as well as automotive plastics manufacturing, food canning, and metalworking workplaces. The influential study has led trade unions, politicians and charities in the United Kingdom and Canada to demand health and safety regulatory changes and further research.
A number of studies have been produced by the multidisciplinary, multinational team, in which Professor Matthias Beck plays a lead role. The main study was published and released to the media in 2012 (Brophy et al. 2012b); so far it has attracted more than 16,000 downloads and over 220 media references.
There are currently 2 million cancer survivors in the UK. This is predicted to become 6 million by 2050 — by which time more than 50% of the UK population are expected to have experienced a cancer diagnosis. Our research and expertise have been central to the creation of the Department of Health's National Cancer Survivorship Initiative (NCSI), and framing policy more widely to respond to this challenge. It has provided evidence of the wide-ranging impact of the disease following cancer treatment, and has led to new models of cancer aftercare being implemented across the UK and internationally. Our research has linked directly to policy and practice through Professor Jessica Corner's membership of the NCSI Steering Group, as co-chair of the Department of Health's Cancer Patient Experience Advisory Group, and through our partnership with Macmillan Cancer Support.
Two books and review/research articles in Italian have disseminated the findings from the underpinning research on creating false autobiographical memories and the dangers of inadequate interviewing techniques. This work has critically increased awareness in the Italian legal system amongst both barristers and judges, to the point of shaping the practice of interviewing witnesses in that country. It has also informed all verdicts on child sexual abuse by the Supreme Court of Cassation.
Research on the environmental safety and toxicity of nanomaterials in fishes has had a global impact across both government and industry contributing to:
(i) Consensus building on biological effects allowing regulatory agencies/governments to make proper decisions on the hazard of nanomaterials to farmed fish and wildlife.
(ii) Critical evaluation of the internationally agreed process of toxicity testing to determine whether the current legislative test methods are fit for purpose and acceptable to the aquaculture industry.
(iii) Identification of national/international research priorities and policies via work with the OECD and the US Government.
(iv) Influencing government policy to support training and information for industry.
Research has linked employee wellbeing to employee motivation and engagement, which can in turn drive increases in productivity and improved levels of product/service delivery. This case study illustrates how academic research and enterprise-based activity, through a university spinout company, has helped to create a significant positive impact on promoting and improving employee wellbeing. This has been achieved across a variety of national and international organisations, including several high profile private and public organisations, involving over 50,000 employees across Europe. This has resulted in a number of positive outcomes such as national and international awards in the area of HR as well as increased employee engagement and reduced employee absenteeism.
Work by University of Stirling staff has contributed directly to improved wildlife resource management in the Central African region. Innovative research into the status and trends of key wildlife populations, ecological impacts, resource harvests and trade, drivers of resource use and assessing management success have contributed directly to new thinking on the issue, revisions of laws and policy and to success in attracting foreign aid for management issues. Stirling staff members now advise the Government of Gabon on resource management policies, National Park management and biodiversity issues.
This case study concerns the impact of Plymouth University research relating to farmed fish diets, which led to changes to EU legislation with respect to two types of ingredients: animal proteins and probiotics. The impact of the reintroduction of certain animal proteins in farmed fish feeds (previously banned to protect human health) and to the authorization of a probiotic as a feed additive, involved industry investment in research, have reduced the environmental impact of farmed fishing, improved competitiveness, enhanced yield and quality and improved fish health and survival.
Bladder cancer is the fifth most common form of cancer, with over 70% of cases presenting as non-muscle invasive bladder carcinomas (NMIBC). Research in the Institute of Cancer Therapeutics at the University of Bradford led to the evaluation of Apaziquone (EO9) in phase II clinical trials against high risk NMIBC in The Netherlands, and two multi-centre phase III clinical trials involving 106 centres across the USA, Canada and Europe. A total of 1,746 patients with low or high risk NMIBC received EO9 and significant reductions in the rates of recurrence at two years have been reported. Our research has impacted upon the health and welfare of patients with NMIBC.
The core target in the government's national strategy for cancer control in England is to `save 5,000 lives a year by 2015'. This target was taken directly from research done by LSHTM showing that 10,000 cancer-related deaths per annum would be avoidable if five-year relative survival were as high as the highest levels observed in Europe. Current government strategy is entirely focused around `halving the gap' in avoidable premature cancer deaths identified in this research, which also forms the basis for England's National Awareness and Early Diagnosis Initiative.
This case study illustrates the development of novel research materials designed to improve quality of life and performance in different populations. Impact has been achieved through the use of research findings in professional practice, formulation of health-related policies and in the development of new indicators of health and well-being. RCSEP research has been used by international and national health-service organisations (e.g., European League Against Rheumatism, Evidence NHS), industrial establishments (e.g., ArtEZ Conservatoire, Netherlands; Royal Ballet), national governing bodies (British Heart Foundation), and professional bodies (e.g., Dance UK, International Association of Dance Medicine & Science).