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The growth and performance of Biofocus Galapagos Argenta (BGA) and Pulmagen Therapeutics (PT) are underpinned by research from the Imperial-based TeknoMed project that started in 1997. BGA was formed in 2010 through the acquisition of Argenta Discovery (AD) by Biofocus Galapagos for €16.5 million and is one of the world's largest drug discovery service organisations with 390 plus employees and turnover of €135 million [section 5, A]. PT was formed as a separate company to own the complete AD drug pipeline. It develops new medicines to treat asthma, cystic fibrosis and allergic diseases. In 2011 BGA signed agreements with PT for an initial £6million fee and with Genentech for £21.5million.
This case study concerns research around public injecting and risks and has been led by Prof Coomber in partnership with Drug and Alcohol Action Teams (DAATs) in Plymouth, Barking and Dagenham, and Southend. The exploration and analysis of public injecting activity has impacted upon the policy and practice of all three DAATs. The research has led to the improved management of an environmental risk and hazard, impacted upon the planning of drug support services, and led to a change in strategy amongst drug agencies in the three locations.
There is a strong tradition of qualitative research with children and young people at The University of Northampton. The Centre for Children and Youth (CCY) was constituted in 1997 and has completed fifty research projects funded by RCUK, national agencies and charities, and Local Authorities and service-providers. This case study focuses upon CCY's research on children and young people's participation in decision-making. This work has produced regional, national and international impacts: our evidence-based guidance has been influential and widely-employed within a broad, international shift towards the involvement of children and young people in decision-making in diverse educational, planning and policy contexts. In particular, this case study evidences CCY's transformative impacts upon the design of spaces for children and young people in educational and urban planning settings.
The social enterprise Mapping for Change (MfC) was established to make use of participatory mapping knowledge and software created through research at UCL. Since 2009, MfC has secured more than 20 contracts worth in excess of £435,000, and has delivered over 30 projects in many communities, directly engaging more than 5,000 people and reaching far more online and indirectly. Its projects have increased community engagement in the local environment, led to new environmental monitoring by local authorities and stimulated policy debate about noise and air pollution.
Language and communication disorders affect about 7% of children in countries where assessments are undertaken such as the UK and USA. Difficulties with language and communication severely limit children's social participation, school attainment and life chances, with repercussions for their families and wider society. Research at City University London has had major impacts on clinical and educational policy and practice and the support available to children of all ages with language and communication needs. For example:
It has led to a validated tool for school-based professionals working with deaf children to identify, monitor and evaluate the needs of those with poor language skills.
This case study comprises a set of qualitative and quantitative analyses of contemporary right-wing extremism in Britain. This research has been extended beyond academia to non-academic beneficiaries in Britain and continental Europe. The research has informed public debate amongst civil society (as indicated by take-up in NGO reports and the media). It has informed policy development (as evidenced by participation in Government advisory processes and through expert advice to Government). The research has also responded to personal and professional development needs of young people. Impact has derived from the quality of the underpinning research and from a variety of external engagement and knowledge transfer activities.