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A Wearable Light Source for Ambulatory Treatment of Skin Cancer and Acne

Summary of the impact

Impact: Health and Economic Gains:

Research has led to a wearable light source that provides a new way of treating many skin cancers and acne. The treatment is safe, convenient, and easy to use bringing benefits to patients and healthcare providers. In addition it brings economic benefits to Ambicare Health Ltd, the company commercialising it.

Significance

For skin cancer treatment, the device gives effective treatment with much reduced pain. The simplified treatment procedure allows more patients to be treated in a clinic session. For acne, the device provides a convenient at-home treatment without the application of drugs or chemicals.

Beneficiaries:

Skin cancer and acne sufferers, the clinics that treat them and Ambicare Health Ltd.

Attribution:

The work was led by Professor Ifor Samuel (PHYESTA) working with Professor James Ferguson (Ninewells Hospital, Dundee).

Reach:

The wearable light source has changed treatment in the UK and the Netherlands. The skin cancer treatment is in regular use at more than 25 clinics, and the acne treatment at more than 250 clinics.

Submitting Institutions

University of St Andrews,University of Edinburgh

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Chemical Sciences: Macromolecular and Materials Chemistry
Engineering: Materials Engineering
Technology: Nanotechnology

Light-emitting Dendrimers

Summary of the impact

Impact: Economic
The light-emittingdendrimers are a new class of materials for organic light-emitting diodes, a major display technology. They have been commercialised by Cambridge Display Technology (CDT), the leading developer of polymer light-emitting diodes.

Significance
Light-emitting dendrimers provided a breakthrough in the efficiency of organic light emitting diode (OLED) materials deposited from solution. This enabled the convenience of solution-processing to be combined with high efficiency, and enabled solution-processed materials to compete with evaporated materials.

Beneficiaries
CDT, display manufacturers around the world and display users.

Attribution
The research was performed by Professor Samuel in collaboration with Professor Burn of the University of Oxford.

Reach
Materials based on light-emitting dendrimers are manufactured by Sumitomo Chemical in Japan and supplied to global displays manufacturers.

Submitting Institutions

University of St Andrews,University of Edinburgh

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Chemical Sciences: Inorganic Chemistry, Macromolecular and Materials Chemistry
Engineering: Materials Engineering

A New Manufacturing, Research and Development Centre for e2v

Summary of the impact

Our research on semiconductor materials and devices has led to the establishment by e2v Technologies of a combined manufacturing, research and development facility within the School of Physics and Astronomy. We have adapted and transferred device simulation software to e2v, and have provided epitaxially-grown semiconductors and access to fabrication facilities which have been used in their manufacturing processes. Devices fabricated within the facility, which was opened in 2011, have generated sales of £7M for e2v. This initiative has also led to shifts in the investment priorities of e2v, and mitigated risks to the company arising from import restrictions associated with the US International Traffic in Arms Regulations (ITAR).

Submitting Institution

University of Nottingham

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Atomic, Molecular, Nuclear, Particle and Plasma Physics
Chemical Sciences: Physical Chemistry (incl. Structural)
Engineering: Materials Engineering

Commercialisation of Ferroelectric Liquid Crystal over Silicon Microdisplays

Summary of the impact

Impact: Economic gains

PHYESTA research has led to the setting up of a company now known as ForthDD. Since 2008 it has increased its annual revenue by more than 25% to around US $5M, and its global workforce from 25 to 35. It has released new products directly underpinned by PHYESTA research as recently as October 2012.

Significance:

A consortium involving PHYESTA staff in collaboration with Edinburgh's School of Engineering and five industrial partners realised the world's first high-resolution ferroelectric liquid crystal over silicon (FLCOS) microdisplay. This digital display attracted investment from the UK, Taiwan, and USA of over $40m, and was taken forward to production by MicroPix, MicroVue, and Forth Dimension Displays.

Reach:

ForthDD now has offices in Valencia, USA, and Berlin, Germany. The company designs, develops and manufactures single chip microdisplays used in the demanding near to eye (NTE) training and simulation systems, HD video camera viewfinders, medical imaging systems and virtual reality and head-mounted displays.

Beneficiaries:

ForthDD, its customers and business partners (e.g. in the medical imaging sector).

Attribution: This work was led within PHYESTA by Professor David Vass involving PHYESTA and done in collaboration with Edinburgh's School of Engineering.

Submitting Institutions

University of St Andrews,University of Edinburgh

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Other Physical Sciences
Engineering: Materials Engineering
Technology: Communications Technologies

Organic solid state lighting: building a full commercial supply chain in the UK (Polymer Lighting)

Summary of the impact

Interdisciplinary research on a new class of organo-metallic light emitting polymers showed that they could produce white light very efficiently. A consortium of the University and Industry (predominantly Thorn Lighting, the largest lighting manufacturing employer in the North East) developed and patented these into a viable alternative to mercury vapour fluorescent lights with a £4.3M grant from the DTI with matched funding from industry. The companies are investing in scaling this up to a full commercial supply chain, supported by a £4M grant from the Technology Strategy Board. The success of the project helped BIS secure £20.5M to support Plastic Electronics in the UK, creating 26 jobs, and was cited as a factor in the Thorn decision not to close down its North East site, safeguarding 600 jobs.

Submitting Institution

University of Durham

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Atomic, Molecular, Nuclear, Particle and Plasma Physics
Chemical Sciences: Macromolecular and Materials Chemistry
Engineering: Materials Engineering

Cavendish Kinetics

Summary of the impact

University of Cambridge research led to the creation of spin-out company, Cavendish Kinetics which developed a micro electro mechanical (MEMS) process technology that allows MEMS devices to be fabricated in a standard silicon foundry. The company is now producing RF MEMS technology for mobile phone applications allowing faster data transfer and lower power consumption. It initially developed a non-volatile memory product for harsh environments. The company has provided more than 350 person years of highly skilled employment (of which 140 person years are within the period) at offices in the US, UK, the Netherlands, and Korea. It has developed a large patent portfolio and raised tens of millions of US dollars in VC funding.

Submitting Institution

University of Cambridge

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Engineering: Biomedical Engineering, Electrical and Electronic Engineering, Materials Engineering

Fabrication of 3D electro-optic circuits by printing (FAB-3D)

Summary of the impact

Prof Silver's research on the development of the technology to fabricate 3D electro-optic circuits via ink-jet and screen printing has provided a more sustainable solution to conventional back-lit posters (energy saving up to 75%) and printed displays. Due to the flexibility of the components (they can be printed in any shape or design) and low maintenance (battery operational), the technology has been commercially exploited by several industrial collaborators. Johnson Matthey have used Brunel research to gain knowledge of the market and supply chain, to sell silver and palladium nano-particles for ink-jet printing and to inform the investment of around £2M on R&D in this area. Intrinsiq Materials Ltd successfully marketed copper-based inks for ink-jet printing of ACEL displays, allowing the company to employ 22 additional staff. In addition, they have secured $4M of venture capital investment to develop the technology. Printed Electronics Ltd have secured £8.6M of investment to develop a high-volume supply chain for printed electronics, and have employed an additional 9 staff within the company. As a result of working with Brunel, Keeling and Walker have begun to sell ink that contains antimony-doped tin oxide nano-powders.

Submitting Institution

Brunel University

Unit of Assessment

Aeronautical, Mechanical, Chemical and Manufacturing Engineering

Summary Impact Type

Technological

Research Subject Area(s)

Chemical Sciences: Macromolecular and Materials Chemistry, Physical Chemistry (incl. Structural)
Engineering: Materials Engineering

The Benefits to Business and Practitioners of Advanced manufacturing by printing of Complex Inks

Summary of the impact

Research in the Welsh Centre for Printing and Coating (WCPC) at Swansea University has produced a sophisticated understanding of the physics of the fluids and interfaces in the printing process, and has pioneered the development of printing with complex, multi-phase inks. The application in volume manufacture made possible by the research has generated significant, multi-million pound, economic impact in the printable electronics and packaging industries, directly leading to the creation of new high technology printed products, including next generation lighting. It has also led to the development of the supply chain for complex functional inks, whilst a comprehensive revision of the ISO standard on ink colorimetric characterisation in 2013 has demonstrable impact on practitioners.

Submitting Institution

Swansea University

Unit of Assessment

General Engineering

Summary Impact Type

Technological

Research Subject Area(s)

Chemical Sciences: Macromolecular and Materials Chemistry, Physical Chemistry (incl. Structural)
Engineering: Materials Engineering

Development of a functional oxide based deposition technology allowing the introduction of new commercial products

Summary of the impact

Research undertaken by the University of Sheffield between 1999 and 2012 in functional oxide thin films was commercialised through knowledge transfer partnerships (KTP) with Ilika Technology. This directly led to over £1M in contracts and subsequent improvements in the commercial viability of the product base of blue-chip companies such as Toshiba, Toyota and Ceramtec and contributed to the increase in Ilika's turnover to ~£2M per annum and a growth in staff from 5 to 35 in 2012. In 2011, Ilika floated on the stock exchange with a valuation of ~£20M. The CEO has personally recognised the role Sheffield has played in establishing Ilika Technology as a limited company and in growing company revenue through contracts with leading multinationals.

Submitting Institution

University of Sheffield

Unit of Assessment

Electrical and Electronic Engineering, Metallurgy and Materials

Summary Impact Type

Technological

Research Subject Area(s)

Chemical Sciences: Inorganic Chemistry, Physical Chemistry (incl. Structural)
Engineering: Materials Engineering

The impact of the production and characterisation of graphene

Summary of the impact

The isolation and characterisation of graphene by Geim and Novoselov demonstrated its potential to underpin disruptive technological change across an incredibly broad range of industries. This resulted in rapid global uptake of new technologies in the REF period, with at least $200m recent commercial investment in graphene production. Blue-chip companies have also made significant investments leading to the generation of 7740 industrial patents. The first set of graphene-based products has reached the market with revenues already exceeding $10m per month. This commercial activity has been matched by global shifts in public research and innovation funding of at least $2.4bn, as governments have moved to facilitate graphene research and commercialisation.

Submitting Institution

University of Manchester

Unit of Assessment

Physics

Summary Impact Type

Technological

Research Subject Area(s)

Physical Sciences: Condensed Matter Physics
Chemical Sciences: Inorganic Chemistry
Engineering: Materials Engineering

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