Summary of the impact

Short Term Conflict Alert systems are used by NATS to alert air traffic controllers to the risk of aircraft becoming dangerously close. This research has provided the means to enhance international air traffic safety by automatically optimising STCA systems so as to simultaneously maximise the number of alerts raised in response to truly dangerous situations, while, at the same time, minimising the number of false alerts. This has been achieved by developing multi-objective evolutionary algorithms to automatically locate the Pareto front describing the optimal trade-off between the numbers of true and false positives. The optimiser is described by NATS as "an outstanding improvement to our safety" [KTP-1395, final report].

Summary of the impact

Targeted Projection Pursuit (TPP) — developed at Northumbria University — is a novel method for interactive exploration of high-dimension data sets without loss of information. The TPP method performs better than current dimension-reduction methods since it finds projections that best approximate a target view enhanced by certain prior knowledge about the data. "Valley Care" provides a Telecare service to over 5,000 customers as part of Northumbria Healthcare NHS Foundation Trust, and delivers a core service for vulnerable and elderly people (receiving an estimated 129,000 calls per annum) that allows them to live independently and remain in their homes longer. The service informs a wider UK ageing community as part of the NHS Foundation Trust.

Applying our research enabled the managers of Valley Care to establish the volume, type and frequency of calls, identify users at high risk, and to inform the manufacturers of the equipment how to update the database software. This enabled Valley Care managers and staff to analyse the information quickly in order to plan efficiently the work of call operators and social care workers. Our study also provided knowledge about usage patterns of the technology and valuably identified clients at high risk of falls. This is the first time that mathematical and statistical analysis of data sets of this type has been done in the UK and Europe.

As a result of applying the TPP method to its Call Centre multivariate data, Valley Care has been able to transform the quality and efficiency of its service, while operating within the same budget.

Summary of the impact

The research improves digital data archives by embedding computation into the storage controllers that maintain the integrity of the data within the archive. This opens up a number of possibilities:

• Data analysis can be automated and incorporated into the archiving process;
• The approach improves the archiving of all types of digital objects, from television broadcasts to genomes;
• The approach can be applied to distributed data and to datasets that are too big for traditional approaches.

This has impact on three different classes of beneficiary:

• Providers of national data infrastructure in the UK and US, who are incorporating Cheshire 3 into national data repositories;
• Data Users, such as Astra Zeneca, RAI, Sanger Institute, who are using Cheshire 3 to extract valuable information from their data;
• Equipment vendors, such as NetApp, Xerox and Bellerophon Mobile, who are developing commercial systems that will use Cheshire 3.

Summary of the impact

Deployment of robust diagnostic techniques developed at the University of Strathclyde has improved the analysis of reactor core data and has directly supported the Safety Case for continued and extended operation of the Advanced Gas-cooled Reactor nuclear power stations in the UK. The new diagnostic techniques have been used on a daily basis since 16/5/2008 (BETA) and 5/3/2009 (IMAPS) in four power stations: 1) providing improved support and confirmation of the manual assessment of reactor core data by graphite engineers; 2) informing and advising power station personnel making strategic decisions on channels requiring inspection during statutory outages, and 3) providing evidence and increased confidence for the monitoring stage of station Safety Cases.

Summary of the impact

Two Knowledge Transfer Partnership projects, carried out between 2006 and 2009, between an e-commerce marketplace provider (@UK plc) and the University of Reading, led to the development of two software tools that were launched in 2010. The tools, SpendInsight and GreenInsight, are the first of their kind to use artificial intelligence techniques to handle the extremely challenging data associated with purchasing in large organisations. Since their launch, these tools have been used by @UK plc to identify procurement savings and environmental costs of procurement activities for governments, multi-national corporations, academic institutions and healthcare providers. Over the last three years @UK plc has benefitted from the launch of these products as it has provided them with a competitive advantage over the market place, increased the quality and efficiency of their spend analyses and led to multi-million pound licensing agreements. An analysis of spending in some of the NHS Trust Foundations has led to changes in procurement behaviours that have resulted in hundreds of thousands of pounds saved to date — benefitting not only the NHS, but also taxpayers.

Summary of the impact

KCL research played an essential role in the development of data provenance standards published by the World Wide Web Consortium (W3C) standards body for web technologies, which is responsible for HTTP, HTML, etc. The provenance of data concerns records of the processes by which data was produced, by whom, from what other data, and similar metadata. The standards directly impact on practitioners and professional services through adoption by commercial, governmental and other bodies, such as Oracle, IBM, and Nasa, in handling computational records of the provenance of data.

Summary of the impact

[text removed for publication], a developer of high-precision medical devices, have produced a new data annotation tool ([text removed for publication]) based on research in CSRI on data storage formats and activity recognition for applications within smart home environments. Within [text removed for publication] stereo-based cameras record activities in a specified environment (e.g. kitchen) which are then annotated using user-based pre-configured activity labels (e.g. prepare meal, wash dishes). [text removed for publication] is currently used by [text removed for publication] users and has yielded additional sales worth [text removed for publication]. [text removed for publication] have employed [text removed for publication] additional technical development staff to extend [text removed for publication] functionality, and through an MoU [text removed for publication] now supports automated annotation based on CSRI's research on activity recognition.

Summary of the impact

The research in this case study has pioneered knowledge management technology. It has had major impact on drug discovery and translational medicine and is widely adopted in the pharmaceutical and healthcare industries. The impacts are:

1. The formation of InforSense to commercialise the technology. The company had 150 employees in June 2009 when it merged with IDBS Ltd to create the world's second largest life science informatics company.
2. The results from knowledge management technology and associated software platform have enabled the integration of molecular, imaging, clinical data and analytics, to identify biomarkers for disease identification, treatment selection and side effect prediction.
3. Since 2002 the technology has been deployed by major pharmaceutical companies (including GSK, AZ, Roche, Pfizer, Bayer and Boehringer Ingelheim) and leading healthcare institutions e.g. Mayo Clinic, Harvard Medical School and King's Health Partners, generating significant social, health and economic impact.

Summary of the impact

Researchers in Cambridge have developed a data standard for storing and exchanging data between different programs in the field of macromolecular NMR spectroscopy. The standard has been used as the foundation for the development of an open source software suite for NMR data analysis, leading to improved research tools which have been widely adopted by both industrial and academic research groups, who benefit from faster drug development times and lower development costs. The CCPN data standard is an integral part of major European collaborative efforts for NMR software integration, and is being used by the major public databases for protein structures and NMR data, namely Protein Data Bank in Europe (PDBe) and BioMagResBank.

Summary of the impact

Research at the Transport Safety Research Centre (TSRC) at Loughborough University has led to the development of a new road safety data and knowledge base called the European Road Safety Observatory (ERSO). The European Commission has confirmed in a reference that it has become a standard tool for EU and national level safety policy development and has been praised by the European Parliament. Since being established in 2006 it has been emulated at national level by many EU Member States including the UK, Spain, Czech Republic, Netherlands and France. The ERSO website now receives over 5000 hits each month from road safety policy-makers across the EU. The research, which was led by TSRC researchers, was conducted between 2004 and 2012 and in 2013 was awarded the HRH Prince Michael International Road Safety Award for its impact on road safety.