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The unique application of combinatorial chemistry in materials science at Southampton has directly underpinned the success of University spin-out, Ilika Technologies. Since 2008, the breadth of applications of the research has allowed Ilika:
Between 2008 and 2012, Ilika enjoyed considerable growth, doubling employment to 35 staff, increasing turnover by approximately 25% annually, and floating on the AIM with a market capitalisation of £18.7 million.
The School of Chemistry has a long track record of pioneering and innovative outreach activities aimed at stimulating public interest and understanding in chemistry research and its societal impact. During the period 2008-2013 it successfully communicated to a wide-ranging audience the significance of a series of "firsts" in the areas of nanoscience and materials for energy applications. Using YouTube, Royal Society Summer Science Exhibitions, roadshows and science festivals, this award-winning approach has engaged hundreds of thousands through digital media and thousands more face-to-face, raising public awareness, inspiring interest in science and delivering educational benefits for students and teachers alike.
Novel vapour sorption experimental methods for the characterisation of complex particulate materials have been developed in the Department of Chemical Engineering. This research and expertise resulted in the creation of Surface Measurement Systems Limited (SMS), whose Dynamic Vapour Sorption (DVS) and Inverse Gas Chromatography (IGC) instruments are now found in >500 laboratories around the world. They are recognised standard research and development tools in the global pharmaceutical industry (DIN 66138). SMS has contributed >270 man-years of employment and generated £27M of turnover, whilst SMS instruments have generated over £300M of economic value, over the REF period.
The technology in this impact study is based on organofunctionalised silica materials that can address market needs for high purity in compounds that underpin many areas of the pharma, electronic and medical sectors as well as the recovery of limited resources such as precious metals that are used in diverse industries. Since the launch of the product portfolio in 2006, the materials have become embedded in purification or recovery steps in commercial production processes of leading mining (South Africa), pharmaceutical (UK) and petrochemical (Germany) companies and make a significant impact on the business of these companies as well as limiting waste of limited resources.
Material characterisation research in the UOA has helped Orchid Cellmark Europe Ltd (Cellmark) to deliver forensic services to 85% of the police forces in England and Wales. The work of the UOA has helped Cellmark to participate successfully in National Forensic Framework tendering exercises and to double their market share. The work of the UOA in partnership with Cellmark has been accredited by the UK Accreditation Service and the UOA now provides an average of 360 forensic glass analyses and 60 gunshot residue analyses to Cellmark each year. These analyses have secured, amongst others, convictions for perpetrators of serious gun crime.
The University of Nottingham's School of Chemistry has developed a novel method of incorporating thermally or chemically labile biologically active substances into polymers. This has been achieved by using supercritical carbon dioxide as a medium for the synthesis and modification of polymeric materials. The method has been employed as the basis for new drug-delivery devices whose viability in the healthcare sphere has been confirmed by patient trials. The spin-out company, Critical Pharmaceuticals Ltd, has delivered a range of economic benefits, including job creation, the securing of millions of pounds' worth of investment and a number of revenue-generating research collaborations.
Cardiff University, through developing and patenting a commercially viable synthetic route to a catalyst, has enabled the application of a new process, the Alpha Process, for the production of methyl methacrylate (MMA), a key commodity precursor to Perspex. The Alpha Process has had economic and environmental impacts.
Lucite International, the world's leading MMA producer, has invested in major Alpha Process production facilities in Singapore and Saudi Arabia, benefitting from a production route which is more efficient, more reliable and cheaper than conventional routes.
The Alpha Process also brings environmental benefits, as it does not rely on the use of corrosive and toxic feedstocks, such as hydrogen cyanide, which are associated with conventional MMA processes.
In 2012, it is estimated the $145bn was invested in solar photovoltaic technology. Dye-Sensitized Solar Cells (DSC) are expected to play an increasing role in renewable energy generation over the next decade and beyond, but several practical issues need to be overcome to facilitate large-scale economic production. Fundamental research at Bangor has laid the ground for collaborative work with industry which has overcome several of the key production constraints in their manufacture, increasing production speed and efficiency and substantially reducing costs. As a result, we have developed a Technology Roadmap with a major multinational partner (TATA) which has led to significant investment in plant and to the production of pilot products in the form of photovoltaic roofs, currently undergoing outdoor testing.
Durham Chemistry has a long history of research in cutting edge crystallographic methods and innovative instrument design which has led to the commercialisation of scientific apparatus and software with significant sales value. Durham-developed apparatus and crystallographic software are used globally by both industry and academia. Autochem2, for example, is sold exclusively to Agilent via the spin-out company OlexSys, and hundreds of researchers rely on Durham's contributions to the Topas software pacakge. Crystallographic research for pharmaceutical and other companies, research-based consultancy, commercial analytical services and provision of international PhD+ level training schools have led to further significant impact.
This case study describes the invention, development and subsequent commercial application of the floating low-energy ion gun (FLIG), a key enabling technology for high-resolution depth profiling, in particular of semiconductor devices. Following its invention at the University of Warwick, the FLIG was commercialised and now plays an important role in the semiconductor industry as a key analytical instrument. Intel and its competitors have used the FLIG in developing specific technologies, such as the PentiumTM, XeonfTM and CoreTM i7 processors. Its impact extends beyond the electronics industry to consumers worldwide since the FLIG has played a key role in the development of multicore processors for personal computers, intense low-energy lighting for automotive and civil engineering, mobile telecommunications technology, and many other areas of advanced electronic, and other material, technologies. This invention has also led directly to an ISO standard for depth resolution.