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3D scanning technology has enabled multiple opportunities for innovation in diverse areas such as manufacturing, design, and the arts. However, full utilisation of this technology requires not just the scanning hardware, but accompanying software that can build meaningful, editable models. This development has been pioneered by research conducted in the School of Computer Science and Informatics, at Cardiff University. Innovative algorithms for reverse engineering and digital shape reconstruction were devised that enabled the reconstruction of complex computer aided design (CAD) models from data captured by 3D scanners. The algorithms have been endorsed by Geomagic Inc, a market leading American software corporation (recently acquired by 3D Systems), that has subsidiaries in Europe and Asia and global distributors, and incorporated into their software product suite. This is accessed by nearly 10,000 licensed users worldwide, who have applied the product for industrial applications including aerospace and automotive engineering, product design, cultural heritage preservation, and healthcare. Accordingly, the impacts claimed are twofold: a) economic gain manifesting in the benefits to Geomagic and a plethora of end users who have utilised the software, b) impact on practitioners and professional services in diverse domains.
Research and Development activity at Cardiff University's Astronomy Instrumentation Group (AIG) has been commercialised and made available to the international market. Sales have been made to fields including bio-molecular spectroscopy for health science, plasma fusion diagnostics for sustainable energy, and remote atmospheric sensing. This has resulted in economic impact through:
Platinum Group Elements (PGE) are critical strategic metals because of their unrivalled applications in catalysts, fuel cells and electronics and cancer therapies. Research and analytical methods developed at Cardiff have impacted on exploration for new PGE deposits, and more efficient processing of PGE ores by international mining companies. A key milestone between 2009 and 2012 was the discovery of a 3 billion year old giant impact crater in West Greenland. This discovery is of major economic significance because all craters previously found in this size class are associated with multi-billion dollar mineral and/or hydrocarbon resources. It led to an intellectual property transaction worth CDN$ 2.1 million and discovery of nickel and PGE deposits in Greenland by North American Nickel Incorporated.
A new family of antiviral agents, bicyclic nucleoside analogues (BCNAs), discovered in Cardiff University has led to a highly potent anti-VZV (shingles) molecule, FV-100. On a worldwide basis more than two million patients are affected by shingles annually. FV-100 has successfully completed Phase II clinical trials, showing it is safe, potent and effective and with clinical advantages over the current standard of care. FV-100 has received more than $30 million in R&D investment, generating patents and creating highly skilled jobs in the UK and the USA, with the parent company currently valued at $397 million. It will enter registration trials in late 2013.
Economic gains by oil and gas companies, improvements in professional practice in hydrocarbon exploration, and environmental benefits from identifying CO2 disposal sites have been achieved through a Cardiff-led consortium with industry. Building on research carried out since 2004, ten of the largest oil companies in the World have contributed to and benefited from understanding how faulted caprocks behave under specific geological conditions. Research at Cardiff has shown which families of faults and fractures make caprocks highly permeable, thus improving Industry's ability to predict if caprocks are able to prevent oil and gas reaching the surface.
We have formulated and executed an extensive public engagement and outreach programme based on our leading technical and scientific involvement in the Herschel Space Observatory, a €1 billion astronomical satellite which was launched in 2009 and operated until April 2013. Herschel observed the Universe at far-infrared and submillimetre wavelengths with three scientific instruments, one of which (SPIRE) was built by an international team led by the Cardiff Astronomy Instrumentation Group, and Cardiff astronomers have been at the forefront in scientific use of Herschel and SPIRE. The beneficiaries of our PR and outreach programme include schoolchildren teachers, the media and the general public. The programme has achieved high exposure and impact locally, nationally and internationally. It provides inspirational personal contact and up-to- date material and information which has stimulated widespread and continuing interest in Herschel and also helped to raise the profile of STEM subjects, ultimately benefiting the economy.
Economic impact is claimed through the growth of the biopharmaceutical spin-out company Q Chip Ltd. During the REF period, this has created 19 new jobs, £7.5M investment, a new Dutch subsidiary (Q Chip BV), and staged-payment, six figure contract sales to four major international pharmaceutical companies.
Q Chip has generated over £928K in contract sales from the pharmaceutical industry from 2008-2012, with further sales of over £1M projected in 2013-14.
Originally established by Professor David Barrow in 2003 from his micro technology research, Q Chip has developed new processes and miniaturised equipment to encapsulate materials, including drugs, within uniform polymeric microspheres as injectable therapeutics.
A Cardiff researcher has led an International 15 year programme resulting in multiple novel findings which have led to changes in the recommended diagnosis and treatment of acquired haemophilia A (AHA). The research has, for the first time, allowed the comparison of immunosuppressive regimens for inhibitor eradication and comparison of the efficacy of treatment strategies to control bleeds. Studies led directly to the production of UK and International guidelines on the management of AHA with 14 of the 18 specific recommendations in the UK guideline being underpinned by Cardiff-led research.
Specialising in Neolithic archaeology, Professor Colin Richards communicates his research beyond academic audiences to the public through museum and community exhibitions, public lectures, newspapers and television. His work has raised local and international awareness of archaeology in Orkney, and tourism through, for example, the reconstruction of archaeological sites thereby contributing to the UNESCO World Heritage status of Orkney. His research has shaped the international profile of these heritage resources through the regional World Heritage research framework, and public presentation of monuments within the World Heritage Area. Richards' research also underpinned specialist evidence at a public windfarm inquiry, the outcome of which contributed to Orkney Island Council windfarm development Policy.
The Rylands Cairo Genizah Project has had impact through its conservation, presentation, and interpretation of an internationally important archive of manuscripts which illuminate all aspects of the history, and the religious, social, and commercial life of the Jews in the Levant from the 9th to the 19th centuries. This collection is of deep interest to the Jewish community in the UK and abroad, and forms part of the cultural capital of this country, where the vast bulk of it is now housed. The project has also had an impact on heritage experts, by developing methods which have been applied to recording and disseminating other cultural assets.