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Economic gains by oil and gas companies, improvements in professional practice in hydrocarbon exploration, and environmental benefits from identifying CO2 disposal sites have been achieved through a Cardiff-led consortium with industry. Building on research carried out since 2004, ten of the largest oil companies in the World have contributed to and benefited from understanding how faulted caprocks behave under specific geological conditions. Research at Cardiff has shown which families of faults and fractures make caprocks highly permeable, thus improving Industry's ability to predict if caprocks are able to prevent oil and gas reaching the surface.
The Zambian Copperbelt is the largest known repository of copper on Earth. Research at the University of Southampton has transformed the exploration landscape in the region, providing the world's mining companies with new opportunities for mineral exploration in Zambia and other sedimentary basins in Africa. This inward investment has contributed to rapid economic growth in Zambia and boosted local employment. Southampton's research model has contributed to the discovery of two world class copper deposits, impacted on the earnings of global mining companies, as well as ensuring a flow of highly skilled geologists from academia to industry.
3D scanning technology has enabled multiple opportunities for innovation in diverse areas such as manufacturing, design, and the arts. However, full utilisation of this technology requires not just the scanning hardware, but accompanying software that can build meaningful, editable models. This development has been pioneered by research conducted in the School of Computer Science and Informatics, at Cardiff University. Innovative algorithms for reverse engineering and digital shape reconstruction were devised that enabled the reconstruction of complex computer aided design (CAD) models from data captured by 3D scanners. The algorithms have been endorsed by Geomagic Inc, a market leading American software corporation (recently acquired by 3D Systems), that has subsidiaries in Europe and Asia and global distributors, and incorporated into their software product suite. This is accessed by nearly 10,000 licensed users worldwide, who have applied the product for industrial applications including aerospace and automotive engineering, product design, cultural heritage preservation, and healthcare. Accordingly, the impacts claimed are twofold: a) economic gain manifesting in the benefits to Geomagic and a plethora of end users who have utilised the software, b) impact on practitioners and professional services in diverse domains.
A new family of antiviral agents, bicyclic nucleoside analogues (BCNAs), discovered in Cardiff University has led to a highly potent anti-VZV (shingles) molecule, FV-100. On a worldwide basis more than two million patients are affected by shingles annually. FV-100 has successfully completed Phase II clinical trials, showing it is safe, potent and effective and with clinical advantages over the current standard of care. FV-100 has received more than $30 million in R&D investment, generating patents and creating highly skilled jobs in the UK and the USA, with the parent company currently valued at $397 million. It will enter registration trials in late 2013.
A Cardiff researcher has led an International 15 year programme resulting in multiple novel findings which have led to changes in the recommended diagnosis and treatment of acquired haemophilia A (AHA). The research has, for the first time, allowed the comparison of immunosuppressive regimens for inhibitor eradication and comparison of the efficacy of treatment strategies to control bleeds. Studies led directly to the production of UK and International guidelines on the management of AHA with 14 of the 18 specific recommendations in the UK guideline being underpinned by Cardiff-led research.
Research and Development activity at Cardiff University's Astronomy Instrumentation Group (AIG) has been commercialised and made available to the international market. Sales have been made to fields including bio-molecular spectroscopy for health science, plasma fusion diagnostics for sustainable energy, and remote atmospheric sensing. This has resulted in economic impact through:
Economic impact is claimed through the growth of the biopharmaceutical spin-out company Q Chip Ltd. During the REF period, this has created 19 new jobs, £7.5M investment, a new Dutch subsidiary (Q Chip BV), and staged-payment, six figure contract sales to four major international pharmaceutical companies.
Q Chip has generated over £928K in contract sales from the pharmaceutical industry from 2008-2012, with further sales of over £1M projected in 2013-14.
Originally established by Professor David Barrow in 2003 from his micro technology research, Q Chip has developed new processes and miniaturised equipment to encapsulate materials, including drugs, within uniform polymeric microspheres as injectable therapeutics.
In 2012, it is estimated the $145bn was invested in solar photovoltaic technology. Dye-Sensitized Solar Cells (DSC) are expected to play an increasing role in renewable energy generation over the next decade and beyond, but several practical issues need to be overcome to facilitate large-scale economic production. Fundamental research at Bangor has laid the ground for collaborative work with industry which has overcome several of the key production constraints in their manufacture, increasing production speed and efficiency and substantially reducing costs. As a result, we have developed a Technology Roadmap with a major multinational partner (TATA) which has led to significant investment in plant and to the production of pilot products in the form of photovoltaic roofs, currently undergoing outdoor testing.
Specialising in Neolithic archaeology, Professor Colin Richards communicates his research beyond academic audiences to the public through museum and community exhibitions, public lectures, newspapers and television. His work has raised local and international awareness of archaeology in Orkney, and tourism through, for example, the reconstruction of archaeological sites thereby contributing to the UNESCO World Heritage status of Orkney. His research has shaped the international profile of these heritage resources through the regional World Heritage research framework, and public presentation of monuments within the World Heritage Area. Richards' research also underpinned specialist evidence at a public windfarm inquiry, the outcome of which contributed to Orkney Island Council windfarm development Policy.
The results of commissioned research by Aberystwyth University (AU) have shaped decision-making that led to the relocation of refugee Roma, Ashkali and Egyptian (RAE) communities in Mitrovica, northern Kosovo. In 2009/2010 AU research unequivocally identified the source of elevated lead (Pb) levels in soils that had been blamed for high infant and adult mortality rates in RAE refugee camps, and established that Roma Mahalla had sufficiently low soil Pb levels to permit the construction of a purpose-built housing development for the RAE communities. Following the relocation of the RAE families to Roma Mahalla in 2010/2011 there has been a significant reduction in blood Pb levels in children with no reported deaths attributable to Pb poisoning. This AU research project has had a demonstrable positive impact on life quality and human health of the resettled RAE communities living in Mitrovica.